All the following statements regarding histones, the proteins used in packaging of DNA, are correct except:
1.
They are rich in amino acids - Lysine and Arginine.
2.
They carry a positive charge on the side chain.
3.
They are organized to form a unit of 8 molecules.
4.
The pH of histones is slightly acidic.
Subtopic: Â DNA Packaging |
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A double stranded DNA molecule from a bacteriophage is found to consist of 23% adenine bases. The expected percentage of guanine in this DNA molecule will be:
| 1. | 23 % | 2. | 27 % |
| 3. | 46 % | 4. | 54 % |
Subtopic: Â The DNA |Â DNA Double Helix |
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In the human genome:
| 1. | the total number of genes are about 60000 |
| 2. | less than 2 percent of genome does not code for proteins |
| 3. | repeated sequences are rarely found |
| 4. | SNPa occur at about 1.4 million locations |
Subtopic: Â Human Genome Project |
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Identify the incorrect match:
| mRNA codon | Amino acid | |
| 1. | AUG | Methionine |
| 2. | GGG | Glycine |
| 3. | UGA | Tryptophan |
| 4. | UAG | None; it is a stop codon |
Subtopic: Â Genetic Code |
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Identify the incorrect statement:
| 1. | Transcription and translation can be coupled in prokaryotes |
| 2. | DNA is a better genetic material than RNA |
| 3. | It is the presence of structural gene in a transcription unit that defines the template and coding strands |
| 4. | RNA polymerase III is responsible for transcription of tRNA, 5srRNA and snRNAs |
Subtopic: Â Transcription |
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The genetic code is:
| 1. | triplet, degenerate, nearly universal and read in a contiguous fashion |
| 2. | triplet, degenerate, nearly universal and read in an overlapping fashion |
| 3. | doublet, degenerate, nearly universal and read in a contiguous fashion |
| 4. | triplet, ambiguous, totally universal and read in a contiguous fashion |
Subtopic: Â Genetic Code |
 84%
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Consider the given statements:
| I: | Griffith discovered the process of bacterial transformation. |
| II: | Hershey and Chase unequivocally proved that DNA is the genetic material. |
| III: | Meselson and Stahl showed that DNA replicated semi-conservatively. |
| 1. | Only I and II are correct |
| 2. | Only I and III are correct |
| 3. | Only II and III are correct |
| 4. | I, II and III are correct |
Subtopic: Â DNA Replication |Â Search for Genetic Material |
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The lac operon can be described as:
| 1. | an inducible operon with a positive regulation by the repressor protein |
| 2. | an inducible operon with a negative regulation by the repressor protein |
| 3. | a repressible operon with a positive regulation by the repressor protein |
| 4. | a repressible operon with a negative regulation by the repressor protein |
Subtopic: Â Gene Regulation: Lac Operon |
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Which of the following is not a salient feature of the human genome?
| 1. | Less than 2 percent of the genome codes for proteins |
| 2. | Chromosome 1 has most genes [2969] and the Y has the fewest [231] |
| 3. | The function of almost all the discovered genes is known |
| 4. | Repeated sequences make up a very large portion of human genome |
Subtopic: Â Human Genome Project |
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Read the following statements and choose the set of correct statements:
Choose the correct answer from the options given below:
1. (a), (c), (e) only
2. (b), (d), (e) only
3. (a), (c), (d) only
4. (b), (e) only
| (a) | Euchromatin is loosely packed chromatin. |
| (b) | Heterochromatin is transcriptionally active. |
| (c) | Histone octomer is wrapped by negatively charged DNA in nucleosome. |
| (d) | Histones are rich in lysine and arginine. |
| (e) | A typical nucleosome contains 400 bp of DNA helix. |
1. (a), (c), (e) only
2. (b), (d), (e) only
3. (a), (c), (d) only
4. (b), (e) only
Subtopic: Â DNA Double Helix |Â DNA Packaging |
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