Suppose you are provided with an actively dividing culture of E. coli bacteria to which radioactive thymine has been added. What would happen if a cell replicates once in the presence of this radioactive base?
1. One of the daughter cells, but not the other, would have radioactive DNA.
2. Neither of the two daughter cells would be radioactive.
3.  All four bases of the DNA would be radioactive.
4. DNA in both daughter cells would be radioactive.
 

Subtopic:  DNA Replication |
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Level 3: 35%-60%
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Which of the following provides some evidence that RNA probably evolved before DNA?
1. RNA polymerase uses DNA as a template.
2. RNA polymerase makes a single-stranded molecule.
3.  RNA polymerase does not require localized unwinding of the DNA.
4.   DNA polymerase uses primer, usually made of RNA
Subtopic:  DNA vs RNA as Genetic Material |
 62%
Level 2: 60%+
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A section of double stranded DNA is composed of 41% adenine bases. What is the percentage of cytosine bases in this section of DNA? 
1. 18% 
2.  9%
3. 36% 
4. 82% 
Subtopic:  DNA Double Helix |
 90%
Level 1: 80%+
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Genes involved in turning on (or) off the transcription of a set of structural genes are called 
1. Operator genes 
2. Polymorphic genes 
3. Redundant genes 
4. Regulatory genes 
Subtopic:  Gene Regulation: Lac Operon |
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Level 2: 60%+
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Which of the following is the sequence of mRNA transcribed from the below DNA? 
3' - ATCCCAGGTACCAT - 5' 
1. 3' - UAGGGUCCAUGGUA - 5' 
2. 5' - UAGGGUCCAUGGUA - 3' 
4. 3' -TAGGGTCCATGGTA -5' 
4. 5' - TAGGGTCCATGGTA - 3'
Subtopic:  Transcription |
 78%
Level 2: 60%+
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Process of transcription in bacteria involves 
1. Polyadenylation, initiation, termination 
2. Capping, elongation, termination 
3. Elongation, splicing, termination 
4. Initiation, elongation, termination 
Subtopic:  Transcription |
 89%
Level 1: 80%+
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During replication in E.coli, mutations inactivate the gene coding for beta-galactosidase. Which of the following will be affected? 
1. Hydrolysis of glucose 
2. Hydrolysis of lactose 
3. Hydrolysis of galactose 
4. Hydrolysis of xylulose 
Subtopic:  Gene Regulation: Lac Operon |
 84%
Level 1: 80%+
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Match List I with List II
List I List II
A. Frederick Griffith I. DNA replicate semi-conservatively
B. Alfred Hershey & Martha chase II. Cell-free system for protein synthesis
C. Matthew Meselson & Frank Stahl III. Transforming principle
D. Marshall Nirenberg IV. DNA-Genetic material
Choose the correct answer from the following given below:
1. A-III     B-IV      C-I       D-II
2. A-I       B-II       C-III     D-IV
3. A-II      B-III      C-IV     D-I
4. A-IV     B-III      C-I       D-II
Subtopic:  DNA Replication | Search for Genetic Material |
 88%
Level 1: 80%+
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Given below are two statements
I: The process of transcription in eukaryotes with additional complexities -There are at least three RNA polymerases in the nucleus with clear cut division of labor. The RNA polymerase I transcribes rRNAs whereas the RNA polymerase III is responsible for transcription of tRNA, 5S rRNA and snRNAs. The RNA polymerase II transcribes precursor of mRNA and hnRNA.
II: The primary transcripts contain both the exons and introns are non-functional. It is subjected to a process of splicing whereas the introns are removed and exons are joined in a defined order. hnRNA undergoes additional processing called as capping and tailing.
In light of the above statements, choose the most appropriate answer from the options given below
1. Both statement I and statement II are true
2. Both statement I and statement II are false
3. Statement I is true but statement II is false
4. Statement I is false but statement II is true
Subtopic:  Transcription |
 79%
Level 2: 60%+
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In lac operon, operator sequence/region binds with
1. Regulatory gene to switch off the operon
2. Repressor protein to switch on the structural genes
3. Repressor protein to switch off the structural genes
4. Inducer to switch on the operon
Subtopic:  Gene Regulation: Lac Operon |
 64%
Level 2: 60%+
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