Identify the correct statements from the given statements and choose the correct option:

I: Both prokaryotic and eukaryotic mRNAs have a 5' cap.
II: Only prokaryotic mRNAs are polyadenylated at the 3' end.
III: In prokaryotes, transcription is coupled to translation.
IV: In eukaryotes, RNA splicing occurs after the mRNA is transported into the cytoplasm.
V: RNA splicing requires the formation of a spliceosome.
VI: Both prokaryotic and eukaryotic mRNAs are synthesized by RNA polymerase.

1. III, V, and VI only
2. II, III, V, and VI only
3. I, III, V, and VI only
4. I, III, IV, V, and VI only

Subtopic:  Transcription: I | Translation | Translation Mechanism |
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A molecule that can act as a genetic material must fulfill all the following criteria except:

1. It should be able to generate its replica.

2. It should chemically and structurally be stable.

3. It should be able to express itself in the form of Medelian characters.
4. It should provide scope for rapid changes required for evolution.

Subtopic:  Search for Genetic Material |
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Level 1: 80%+
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Histones are rich in:

1. Basic amino acids lysine and arginine

2. Acidic amino acids lysine and arginine

3. Basic amino acids glutamate and aspartate

4. Acidic amino acids glutamate and aspartate

Subtopic:  DNA Packaging |
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On examining a sample of human DNA, it was found that it contains approximately 24 % thymine. Which of the following would be true based on this finding?

1. The amount of adenine in a similar sample of DNA from any human being will be approximately 24 %.

2. The amount of adenine in a similar sample of DNA from any living being will be approximately 24 %.

3. The amount of adenine in a similar sample of DNA from any eukaryotic cell will be approximately 24 %.

4. The amount of adenine in a similar sample of DNA from any mammal will be approximately 24 %.

Subtopic:  Search for Genetic Material:I | Search for Genetic Material: II |
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Which radioactive isotope was used in Meselson and Stahl experiment to prove the semi-conservative mode of DNA replication?
1. 35S 2. 32P
3. 15N 4. None
Subtopic:  Search for Genetic Material |
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Under conditions where methionine must be the first amino acid, what protein would be coded for by the following mRNA?

5'-CCUCAUAUGCGCCAUUAUAAGUGACACACA-3'

1. pro his met arg his tyrlyscys his thr
2. met arg his tyrlyscys his thr
3. met arg his tyrlys
4. met pro his met arg his tyrlyscys his thr
Subtopic:  Translation |
Level 3: 35%-60%

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Which of the following is likely if there is a mutation in the lacY gene of the lac operon in E.coli?

1. The lac genes would be expressed efficiently only in the absence of lactose.
2. The lac genes would be expressed efficiently until the lactose supply in the cell is exhausted.
3. The lac genes would be expressed continuously.
4. Expression of the lac genes would cease immediately.

Subtopic:  Gene Regulation: Introduction |
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Level 3: 35%-60%
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The difference between ATP and the nucleoside triphosphates used during DNA synthesis is that:

1. The nucleoside triphosphates have the sugar deoxyribose; ATP has the sugar ribose.
2. The nucleoside triphosphates have two phosphate groups; ATP has three phosphate groups.
3. ATP contains three high-energy bonds; the nucleoside triphosphates have two.
4. ATP is found only in human cells; the nucleoside triphosphates are found in all animal and plant cells.
Subtopic:  The DNA |
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Which of the following pairs of codons encode the same amino acid?

1.AUG and AUC2.UAA and UAC
3.GUA and GUG4.UAG and UAC

Subtopic:  Translation |
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The salient features of the human genome include all except:
1. About 1.4 million SNP locations
2. Functions known for less than 50% of the discovered genes
3. The actual number of genes and the initial estimates are remarkable similar
4. More than 98% of genome does not code for proteins

Subtopic:  Human Genome Project |
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