The two polynucleotide strands in a dsDNA molecule are:
 
1. parallel and identical
2. anti-parallel and identical
3. parallel and complementary
4. anti-parallel and complementary

Subtopic:  DNA Double Helix |
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Level 1: 80%+
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The allele of a gene locus that is least frequent, in a population, has a frequency greater than 0.01. Such a gene locus will be called:
1. Redundant 2. Degenerate
3. Polymorphic 4. Hot spot
Subtopic:  DNA Fingerprinting |
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In the human genome:
1. there are 3164.7 billion base pairs
2. largest known gene is HbS
3. more than 20 percent part codes for proteins
4. chromosome 1 has most genes
Subtopic:  Human Genome Project |
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In an operon:
I: a polycistronic structural gene is regulated by a common promoter and regulatory genes
II: the regulation is always negative and inducible
 
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic:  Gene Regulation: Lac Operon |
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Level 2: 60%+
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The bacterium Escherichia coli was not used by:
 
1. Fred Griffith, when he discovered bacterial transformation
2. Alfred Hershey and Martha Chase, when they conclusively proved that DNA is the molecule that stores genetic information
3. Matthew Meselson and F. Stahl, when they experimentally proved that DNA replicates semi-conservatively
4. Francois Jacob and Jacques Monod, when they proposed the working of lactose operon
Subtopic:  Search for Genetic Material |
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All the following statements regarding histones, the proteins used in packaging of DNA, are correct except:

1. They are rich in amino acids - Lysine and Arginine.
2. They carry a positive charge on the side chain.
3. They are organized to form a unit of 8 molecules.
4. The pH of histones is slightly acidic.
Subtopic:  DNA Packaging |
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A double stranded DNA molecule from a bacteriophage is found to consist of 23% adenine bases. The expected percentage of guanine in this DNA molecule will be:
1. 23 % 2. 27 %
3. 46 % 4. 54 %
Subtopic:  The DNA | DNA Double Helix |
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In the human genome:
 
1. the total number of genes are about 60000
2. less than 2 percent of genome does not code for proteins
3. repeated sequences are rarely found
4. SNPa occur at about 1.4 million locations
Subtopic:  Human Genome Project |
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Identify the incorrect match:
mRNA codon Amino acid
1. AUG Methionine
2. GGG Glycine
3. UGA Tryptophan
4. UAG None; it is a stop codon
Subtopic:  Genetic Code |
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Identify the incorrect statement:
1. Transcription and translation can be coupled in prokaryotes
2. DNA is a better genetic material than RNA
3. It is the presence of structural gene in a transcription unit that defines the template and coding strands
4. RNA polymerase III is responsible for transcription of tRNA, 5srRNA and snRNAs
Subtopic:  Transcription |
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Level 2: 60%+
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