Choose the correct option regarding Retrovirus:

1.  An RNA virus that synthesises DNA during infection
2.  A DNA virus that synthesises RNA during infection
3.  A ssDNA virus
4.  A dsRNA virus

Subtopic:  Gene Therapy | Molecular Diagnosis |
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Match each item in Column I with one item in Column II and chose your answer from the codes given below.

Column I

Column II

I. RNAi

II. Ribozyme

III. PCR

IV. Monoclonal antibodies

1. Fire and Mello

2. Thomas Cech

3. Kyle Mullis

4. Millstein and Kohler

Codes:

I II III IV
1. 1 2 3 4
2. 2 1 4 3
3. 2 1 3 4
4. 1 2 4 3

Subtopic:  Interference RNA Tech | Molecular Diagnosis |
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Pathophysiology is the:

1. Study of physiology of pathogen

2. Study of normal physiology of the host

3. Study of altered physiology of the host

4. None of the above

Subtopic:  Molecular Diagnosis |
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The first recombinant therapeutic product approved for human use was:

1.Humulin 2.hGH
3.Factor VIII clotting factor4.Erythropoietin

Subtopic:  Gene Therapy | Molecular Diagnosis |
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A fragment of nucleic acid (DNA or RNA) that can be used to identify, usually through autoradiography, specific DNA or RNA molecules bearing the complementary sequence is called:

1.Vector2.Probe
3.Selectable marker4.Reporter gene

Subtopic:  Molecular Diagnosis |
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ELISA is based on the principle of:
1. Antibody opsonization
2. Antigen-antibody interaction
3. Radioactive immune assay
4. Creation of recombinant DNA

Subtopic:  Molecular Diagnosis |
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A hybridization probe used in molecular diagnosis is commonly tagged with a radioactive isotope to allow for its visualization. A common such radioactive isotope that can be used is:

1.60Co2.32P
3.15N4.131I

Subtopic:  Molecular Diagnosis |
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With the help of ELISA, infection by pathogen can be detected by the presence in a sample of:
I. antigens of the pathogen
II. antibodies synthesized against the pathogen
1.Only I2.Only II
3.Both I and II4.Neither I nor II
Subtopic:  Molecular Diagnosis |
 81%
From NCERT
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