Q. No.Recombinant therapeutic [used for treatment] products are available for all the following disorders except:
1. Hemophilia A 2. Pituitary dwarfism 3. Diabetes insipidus 4. Anemia due to renal failure
Electroporation is:
| 1. | the process of separating charged molecules through a gel maintained in an electric field |
| 2. | the process of combining foreign DNA to an electrically charged vector molecule |
| 3. | the process of introducing DNA into cells by the application of high-voltage pulses |
| 4. | the process of protoplast fusion by the application of high-voltage pulses |
A direct target for gene therapy would include all the following cells except:
| 1. | erythrocytes | 2. | muscle fibers |
| 3. | hepatocytes | 4. | vascular endothelium |
Which of the following is a recombinant protein?
| 1. | Beta Galactosidase in E.coli | 2. | Insulin in humans |
| 3. | Somatotropin in humans | 4. | Interferon in E. coli |
The study of all the proteins encoded by the genome of an organism is called :
| 1. | Proteome | 2. | Proteomics |
| 3. | Translation studies | 4. | Genomics |
You want to transform the cells of sugarcane plants with the objective of introducing a disease-resistant gene in sugarcane plants. The best method to achieve this goal would be:
| 1. | The use of a gene gun |
| 2. | Microinjection |
| 3. | Agrobacterium tumefaciens mediation |
| 4. | Delivery of DNA by liposomes |
Match each item in Column I with one in Column II and select the answer from the codes given below:
|
COLUMN I |
COLUMN II |
||
|
A |
First genetically modified crop |
a |
Antibiotic-resistant tobacco plant |
|
B |
First genetically modified food |
b |
Flavr Savr |
|
C |
First genetically modified animal approved for food use |
c |
AquAdvantage Salmon |
|
D |
First genetically modified animal to be commercialized |
d |
GloFish |
Codes :
| A | B | C | D | |
| 1. | a | b | c | d |
| 2. | a | b | d | c |
| 3. | b | a | c | d |
| 4. | b | a | d | c |
ELISA is based on the principle of:
1. Antibody opsonization
2. Antigen-antibody interaction
3. Radioactive immune assay
4. Creation of recombinant DNA
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The first recombinant therapeutic product approved for human use was:
| 1. | Humulin | 2. | hGH |
| 3. | Factor VIII clotting factor | 4. | Erythropoietin |
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How were nematode-specific genes introduced in tobacco plants?
| 1. | Using page DNA | 2. | Using a retrovirus |
| 3. | By gene gun | 4. | Using Agrobacterium tumefaciens |
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