Q. No.Consider the two statements:
I:
Use of genetically modified crops can be a possible solution for minimizing the use of chemicals and fertilizers that are detrimental for the environment.
II:
Genetically modified crops do not require any fertilizers.
1.
Both I and II are correct and II explains I.
2.
Both I and II are correct but II does not explain I.
3.
I is correct but II is incorrect.
4.
Both I and II are incorrect.
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Why does the bacterium Bacillus thuringiensis not affected by the toxins produced by it that can kill arthropods?
| 1. | The toxin inactivated by proteins in the bacterial cells. |
| 2. | The bacterial cell does not have organelles and thus it is harmless. |
| 3. | It is produced as a pro-toxin by the bacterium. |
| 4. | The protein needs post-transcriptional modification possible only in eukaryotic cells. |
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Identify the incorrect statement regarding the use of RNAi for creating transgenic tobacco plants resistant to Meloidogyne incognita:
| 1. | Agrobacterium tumefaciens was used to transform the plant cells |
| 2. | Double-stranded RNA was introduced into the plant cells |
| 3. | Double-stranded RNA was formed in the plant cells that initiated RNAi |
| 4. | A specific mRNA of the nematode was silenced with the help of dsRNA |
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Gene therapy for ADA deficiency has been tried with the help of which of the following vectors?
| 1. | Microinjection | 2. | Liposome |
| 3. | A bacterium | 4. | A retrovirus |
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Alpha-1-antitrypsin was produced in a transgenic sheep, Tracy. This enzyme is used in the treatment of:
| 1. | Emphysema | 2. | Rheumatoid arthritis |
| 3. | Ovarian cancer | 4. | Pancreatitis |
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GM crops have been modified with various traits. Golden rice has been developed by the International Rice Research Institute for:
| 1. | Improved shelf life | 2. | Disease resistance |
| 3. | Herbicide resistance | 4. | Improved nutritional value |
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Transgenic animals used to test the safety of polio vaccine are:
| 1. | Mice | 2. | Monkeys |
| 3. | Rabbits | 4. | Pigs |
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A possible permanent cure for SCID can be:
| 1. | Enzyme replacement therapy, in which functional ADA is given to the patient by injections. |
| 2. | Bone marrow transplantation. |
| 3. | A functional ADA cDNA (using a retroviral vector) introduced into lymphocytes. |
| 4. | Gene isolated from marrow cells producing ADA is introduced into cells at early embryonic stages. |
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RNA interference involves silencing a specific mRNA by:
| 1. | interfering with its post transcriptional modification |
| 2. | not allowing the transport of mRNA from nucleus to cytoplasm |
| 3. | a dsRNA that binds to it and prevents its translation |
| 4. | post translational degradation of the protein |
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The main challenge for production of insulin using rDNA techniques was:
| 1. | to find a suitable host cell that can perform RNA splicing |
| 2. | isolation of a copy of gene from the human DNA |
| 3. | getting insulin assembled into a mature form |
| 4. | downstream processing |
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