Identify the correct statements from the given statements and choose the correct option:

I: Both prokaryotic and eukaryotic mRNAs have a 5' cap.
II: Only prokaryotic mRNAs are polyadenylated at the 3' end.
III: In prokaryotes, transcription is coupled to translation.
IV: In eukaryotes, RNA splicing occurs after the mRNA is transported into the cytoplasm.
V: RNA splicing requires the formation of a spliceosome.
VI: Both prokaryotic and eukaryotic mRNAs are synthesized by RNA polymerase.

1. III, V, and VI only
2. II, III, V, and VI only
3. I, III, V, and VI only
4. I, III, IV, V, and VI only

Subtopic:  Transcription: I | Translation | Translation Mechanism |
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What radioactive isotope was used in Meselson and Stahl experiment to prove the semi-conservative mode of DNA replication?

1. 35S 2. 32P
3. 15N 4. None
Subtopic:  Search for Genetic Material |
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Under conditions where methionine must be the first amino acid, what protein would be coded for by the following mRNA?

5'-CCUCAUAUGCGCCAUUAUAAGUGACACACA-3'

1. pro his met arg his tyrlyscys his thr
2. met arg his tyrlyscys his thr
3. met arg his tyrlys
4. met pro his met arg his tyrlyscys his thr
Subtopic:  Translation |
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Which of the following is likely if there is a mutation in the lacY gene of the lac operon in E.coli?

1. The lac genes would be expressed efficiently only in the absence of lactose.
2. The lac genes would be expressed efficiently until the lactose supply in the cell is exhausted.
3. The lac genes would be expressed continuously.
4. Expression of the lac genes would cease immediately.

Subtopic:  Gene Regulation: Introduction |
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NEET - 2018

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The difference between ATP and the nucleoside triphosphates used during DNA synthesis is that:

1. The nucleoside triphosphates have the sugar deoxyribose; ATP has the sugar ribose.
2. The nucleoside triphosphates have two phosphate groups; ATP has three phosphate groups.
3. ATP contains three high-energy bonds; the nucleoside triphosphates have two.
4. ATP is found only in human cells; the nucleoside triphosphates are found in all animal and plant cells.
Subtopic:  The DNA |
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Which of the following pairs of codons encode the same amino acid?

1.AUG and AUC2.UAA and UAC
3.GUA and GUG4.UAG and UAC

Subtopic:  Translation |
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Griffith wanted to make a vaccine to prevent pneumonia. He injected heat-killed S-strain bacteria into the mice for this purpose. How can a killed bacteria help in making a vaccine?

1. The heat-killed bacteria is a more potent toxin than the live one.
2. Protein denaturation due to heat changes the proteins of the bacterium.
3. Molecules from the cell surface are still intact and can provoke an immune response.
4. DNA molecules can transform other strains of bacteria.
Subtopic:  Search for Genetic Material |
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Griffith's experiment discovered bacterial transformation which in his experiment means:

1. A mutation in the R strain made them virulent.
2. A mutation in the S strain made them non-virulent.
3. A rough strain passed genetic information to a smooth strain.
4. A smooth strain passed genetic information to a rough strain.
Subtopic:  Search for Genetic Material |
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Avery, MacLeod, and McCarty used DNase in their experiment because:

1. It enabled them to isolate pure DNA samples.
2. It enabled them to isolate pure protein samples.
3. This allowed them to demonstrate that removing the DNA prevents transformation.
4. It made sure that RNA will always be present when they attempted to transform the R strain.
Subtopic:  Search for Genetic Material |
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What key observation regarding Garrod'sinborn of metabolism leads to a landmark discovery in molecular biology?

1. Identification of a defective gene in individuals with alkaptonuria.
2. Identification of a defective gene in parents of alkaptonuria patients.
3. Identification of a defective enzyme in individuals with alkaptonuria.
4. Identification of the inheritance pattern of alkaptonuria as autosomal recessive.
Subtopic:  Search for Genetic Material |

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