Production of human protein in bacterial genetic engineering is possible because           
1. Human chromosome replicate bacterial cell
2. Mechanism of gene regulation is identical in humans and bacteria
3. Bacterial cell can undertake RNA splicing
4. Genetic code is universal

Which human chromosome has maximum and minimum genes located on it respectively?

1. X and 1
2. X and Y
3. Y and 1
4. 1 and Y

What defines the template and coding strand of DNA for transcription?
1. Presence of the structural gene in a transcription unit

2. The core RNA polymerase enzyme

3. Presence of the promoter in a transcription unit

4. Presence of 3’ – 5’ TAC codon on the DNA template

The bacterial promotor sequence usually found at the -10 position (ten base pairs upstream of the transcription start site) is:
1. TTGACA
2. TAGACA
3. TATAAT
4. TATTAT

A molecule that can act as a genetic material must fulfill all the following criteria except:

1. It should be able to generate its replica.

2. It should chemically and structurally be stable.

3. It should be able to express itself in the form of Medelian characters.
4. It should provide scope for rapid changes required for evolution.

On examining a sample of human DNA, it was found that it contains approximately 24 % thymine. Which of the following would be true based on this finding?

1. The amount of adenine in a similar sample of DNA from any human being will be approximately 24 %.

2. The amount of adenine in a similar sample of DNA from any living being will be approximately 24 %.

3. The amount of adenine in a similar sample of DNA from any eukaryotic cell will be approximately 24 %.

4. The amount of adenine in a similar sample of DNA from any mammal will be approximately 24 %.

If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is:

5' -ATGAATG-3',

the sequence of bases in its RNA transcript would be;

1. 5'-AUGAAUG-3'

2. 5'-UACUUAC-3'

3. 5'-CAUUCAU-3'

4. 5'-GUAAGUA-3'

The RNA polymerase holoenzyme transcribes:

1. the promoter, structural gene and the terminator region

2. the promoter and the terminator region

3. the structural gene and the terminator region

4. the structural gene only.

To initiate translation, the mRNA first binds to:

1. The smaller ribosomal sub-unit,

2. The larger ribosomal sub-unit

3. The whole ribosome

4. No such specificity exists.

In E.coli, the lac operon gets switched on when:

1. lactose is present and it binds to the repressor

2. repressor binds to operator

3. RNA polymerase binds to the operator

4. lactose is present and it binds to RNA polymerase