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Q. No.What is applicable to both Klinefelter’s syndrome and Turner’s syndrome?
| I. | They result from the non-disjunction of sex chromosomes during gamete formation |
| II. | They can be identified by a karyotype |
| III. | They have 44 autosomes |
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
Subtopic: Sex Aneuploidy - Turner & Klinefelter Syndrome |
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Gynecomastia is an important clinical feature seen in individuals with:
| 1. | Klinefelter's syndrome | 2. | Turner’s syndrome |
| 3. | Oculocutaneous albinism | 4. | Down’s syndrome |
Subtopic: Sex Aneuploidy - Turner & Klinefelter Syndrome |
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Study the given diagram and select the correct option:
| 1. | The karyotype is of an individual suffering from Down’s syndrome |
| 2. | The number of autosomes seen is 43 |
| 3. | The genetic sex of this individual must be female |
| 4. | The fertility will be maintained in this individual |
Subtopic: Sex Aneuploidy - Turner & Klinefelter Syndrome |
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| Assertion (A): | The genetic sex of an individual with Klinefelter's syndrome is female |
| Reason (R): | Only X-chromosome is present in their genotype |
| 1. | Both (A) and (R) are True and the (R) is the correct explanation of the (A) |
| 2. | Both (A) and (R) are True but the (R) is not the correct explanation of the (A) |
| 3. | (A) is True but (R) is False |
| 4. | Both (A) and (R) are False |
Subtopic: Sex Aneuploidy - Turner & Klinefelter Syndrome |
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From NCERT
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Given below [A – E] are suggested causes for the genetic diseases. Select the cause as your answer for the given disease.
| A. | A single nucleotide mutation results in a polar amino acid being substituted by a non-polar amino acid in the polypeptide. |
| B. | Autosomal recessive inborn error of metabolism where mutation renders a key enzyme involved in amino acid metabolism non-functional. |
| C. | X-linked recessive condition is more common in males than in females. |
| D. | Caused by a primary autosomal non-disjunction event. |
| E. | Caused by a non-disjunction event in sex chromosomes in either of the sexes. |
Klinefelter’s syndrome:
| 1. | A | 2. | B |
| 3. | D | 4. | E |
Subtopic: Sex Aneuploidy - Turner & Klinefelter Syndrome |
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