Sickle cell anaemia has not been eliminated from the African population because:

1. It is controlled by recessive genes

2. It is not a fatal disease

3. It provides immunity against malaria

4. It is controlled by dominant genes

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 58%
AIPMT - 2006

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The genetic change shown in the given figure shows the pathogenesis of:

 

1.Phenylketonuria2.Cystic fibrosis
3.Sickle cell anemia4.Thalassemia

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 89%
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Given below is the initial amino acids of the beta chain of a haemoglobin molecule. What will be true about this haemoglobin molecule?

1. The RBCs carrying this molecule will undergo sickling at a high oxygen tension
2. The RBCs carrying this molecule will undergo sickling at a low oxygen tension
3. There will be a quantitative decrease in the synthesis of this molecule
4. This is the normal beta chain of the haemoglobin molecule
Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 58%
From NCERT

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