Q. No.Consider the following statements:
I:
People affected by phenylketonuria are unable to convert tyrosine to phenylalanine.
II:
Alzheimer’s disease results from the accumulation of amyloid protein plaques in the brain.
III:
Klinefelter’s and Turner’s syndromes are the result of nondisjunction of the sex chromosomes in either of the sexes.
Which of the above statements are true?
1.
I and II only
2.
I and III only
3.
II and III only
4.
I, II, and III
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Which of the following would not be a feature seen in a patient with the following karyotype?
1. Many loops on fingertips
2. Congenital heart disease
3. Big and wrinkled tongue
4. Mucus clogging of airways
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Given below is the initial amino acids of the beta chain of a haemoglobin molecule. What will be true about this haemoglobin molecule?
| 1. | The RBCs carrying this molecule will undergo sickling at a high oxygen tension |
| 2. | The RBCs carrying this molecule will undergo sickling at a low oxygen tension |
| 3. | There will be a quantitative decrease in the synthesis of this molecule |
| 4. | This is the normal beta chain of the haemoglobin molecule |
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Match each item in Column I with one in Column II and select the correct answer from the codes given:
|
A |
Codominance |
P |
Progeny resembles both parents |
|
B |
Incomplete dominance |
Q |
Progeny does not resemble either of the parents |
|
C |
Sex determination in Drosophila |
R |
Haplo-diploidy |
|
D |
Sex determination in Honey bee |
S |
Genic balance |
Codes :
| A | B | C | D | |
| 1. | P | Q | R | S |
| 2. | P | Q | S | R |
| 3. | Q | P | R | S |
| 4. | Q | P | S | R |
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Regarding Mendelian disorders :
| 1. | Color blindness is more common in the females of the species. |
| 2. | Sickle cell anemia occurs due to the substitution of valine by glutamic acid in the globin chain of haemoglobin. |
| 3. | Individuals affected by phenylketonuria lack an enzyme that converts tyrosine to phenylalanine. |
| 4. | Thalassemia is inherited as an autosomal recessive trait. |
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The inheritance of colour in wheat Kernel shown below is explained by:
| 1. | Polygenic inheritance | 2. | Pleiotropy |
| 3. | Epistatic interaction | 4. | Multiple allelism |
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Which of a women's grandparents could not be the source of any of the genes on either of her X-chromosomes?
| 1. | Mother's Father. | 2. | Father's Mother. |
| 3. | Mother's Mother. | 4. | Father's Father. |
A woman has an X-linked condition on one of her X chromosomes. This chromosome can be inherited by:
| 1. | Only daughters | 2. | Only sons |
| 3. | Only grandchildren | 4. | Both sons and daughters |
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Match the terms in Column I with their description in Column II and choose the correct option.
| Column I | Column II | ||
| A. | Dominance | 1. | Many govern a single character |
| B. | Codominance | 2. | In a heterozygous organism, only one allele expresses itself |
| C. | Pleiotropy | 3. | In a heterozygous organism, both alleles express themselves fully |
| D. | Polygenic inheritance | 4. | A single gene influences many characters |
| A | B | C | D | |
| 1. | 2 | 3 | 4 | 1 |
| 2. | 4 | 1 | 2 | 3 |
| 3. | 4 | 3 | 1 | 2 |
| 4. | 2 | 1 | 4 | 3 |
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Sickle cell anaemia has not been eliminated from the African population because:
1. It is controlled by recessive genes
2. It is not a fatal disease
3. It provides immunity against malaria
4. It is controlled by dominant genes
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