- 1(current)
Q. No.All the following are examples of competitive enzyme inhibition except:
1. Sulfa drugs used as antibacterial agents
2. Ethyl alcohol used in methyl alcohol poisoning
3. Malonate inhibiting succinic dehydrogenase enzyme
4. Glucose 6 phosphate inhibiting hexokinase in brain
Select the option which is not correct with respect to enzyme action:
1. Substrate binds with enzyme at its active site.
2. Addition of a lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.
3. A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate.
4. Malonate is a competitive inhibitor of succinic dehydrogenase.
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Consider the given two statements:
| I: | In competitive enzyme inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time. |
| II: | The inhibitor always has a much higher affinity for the active site than the normal substrate. |
| 1. | Both I and II are correct and II explains I |
| 2. | Both I and II are correct but II does not explain I |
| 3. | I is correct but II is incorrect |
| 4. | I is incorrect but II is correct |
- 1(current)
Q. No.
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