Q. No.In a DNA strand, two nucleotides are linked through a ___________ linkage to form a dinucleotide.
1. 3’ – 5’ phosphodiester bond
2. 5’ – 3’ phosphodiester bond
3. 1’ N-glycosidic bond
4. Two or three hydrogen bonds
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The bacterial promotor sequence usually found at the -10 position (ten base pairs upstream of the transcription start site) is:
1. TTGACA
2. TAGACA
3. TATAAT
4. TATTAT
Replication in prokaryotes differs from replication in eukaryotes for which of the following reasons?
| 1. | Prokaryotic chromosomes have histones, whereas eukaryotic chromosomes do not. |
| 2. | Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many. |
| 3. | The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes. |
| 4. | Prokaryotes produce Okazaki fragments during DNA replication, but eukaryotes do not. |
Consider the following two statements:
| I: | During transcription, the template strand is read in a 3'-to-5' direction. |
| II: | During transcription, an RNA is transcribed in the 5'-to-3' direction. |
The correct statements is/are:
| 1. | I only | 2. | II Only |
| 3. | I and II | 4. | None |
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Identify the correct statements from the given statements and choose the correct option:
| I: | Both prokaryotic and eukaryotic mRNAs have a 5' cap. |
| II: | Only prokaryotic mRNAs are polyadenylated at the 3' end. |
| III: | In prokaryotes, transcription is coupled to translation. |
| IV: | In eukaryotes, RNA splicing occurs after the mRNA is transported into the cytoplasm. |
| V: | RNA splicing requires the formation of a spliceosome. |
| VI: | Both prokaryotic and eukaryotic mRNAs are synthesized by RNA polymerase. |
| 1. | III, V, and VI only |
| 2. | II, III, V, and VI only |
| 3. | I, III, V, and VI only |
| 4. | I, III, IV, V, and VI only |
A molecule that can act as a genetic material must fulfill all the following criteria except:
1. It should be able to generate its replica.
2. It should chemically and structurally be stable.
3. It should be able to express itself in the form of Medelian characters.
4. It should provide scope for rapid changes required for evolution.
Histones are rich in:
1. Basic amino acids lysine and arginine
2. Acidic amino acids lysine and arginine
3. Basic amino acids glutamate and aspartate
4. Acidic amino acids glutamate and aspartate
On examining a sample of human DNA, it was found that it contains approximately 24 % thymine. Which of the following would be true based on this finding?
1. The amount of adenine in a similar sample of DNA from any human being will be approximately 24 %.
2. The amount of adenine in a similar sample of DNA from any living being will be approximately 24 %.
3. The amount of adenine in a similar sample of DNA from any eukaryotic cell will be approximately 24 %.
4. The amount of adenine in a similar sample of DNA from any mammal will be approximately 24 %.
| 1. | 35S | 2. | 32P |
| 3. | 15N | 4. | None |
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Under conditions where methionine must be the first amino acid, what protein would be coded for by the following mRNA?
5'-CCUCAUAUGCGCCAUUAUAAGUGACACACA-3'
| 1. | pro his met arg his tyrlyscys his thr |
| 2. | met arg his tyrlyscys his thr |
| 3. | met arg his tyrlys |
| 4. | met pro his met arg his tyrlyscys his thr |
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