Q. No.RNAi, as a mechanism of cellular defense, takes place in:
1.
All bacteria
2.
All unicellular organisms
3.
All plants only
4.
All eukaryotic organisms
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How were nematode-specific genes introduced in tobacco plants?
1. Using page DNA
2. Using a retrovirus
3. By gene gun
4. Using Agrobacterium tumefaciens
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The first recombinant therapeutic product approved for human use was:
| 1. | Humulin | 2. | hGH |
| 3. | Factor VIII clotting factor | 4. | Erythropoietin |
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The first clinical gene therapy trial was given in 1990 to a 4 year girl with:
| 1. | Alpha – 1 antitrypsin deficiency |
| 2. | Cystic fibrosis |
| 3. | Adenosine deaminase deficiency |
| 4. | Chronic myeloid leukemia |
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ELISA is based on the principle of:
1. Antibody opsonization
2. Antigen-antibody interaction
3. Radioactive immune assay
4. Creation of recombinant DNA
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The transgenic cow, Rosie, produced milk that:
| 1. | Contained human beta lactalbumin |
| 2. | contained interferons to treat viral infections |
| 3. | contained Alpha – 1 antitrypsin |
| 4. | Is protein enriched |
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Recombinant therapeutic [used for treatment] products are available for all the following disorders except:
| 1. | Hemophilia A | 2. | Pituitary dwarfism |
| 3. | Diabetes insipidus | 4. | Anemia due to renal failure |
Electroporation is:
| 1. | the process of separating charged molecules through a gel maintained in an electric field |
| 2. | the process of combining foreign DNA to an electrically charged vector molecule |
| 3. | the process of introducing DNA into cells by the application of high-voltage pulses |
| 4. | the process of protoplast fusion by the application of high-voltage pulses |
Restriction endonucleases present in bacterial cells provide an advantage to the cell because these enzymes:
| 1. | can identify the mutated sequences on the chromosomal DNA and help in their repair |
| 2. | selectively bind to particular nucleotide sequences that may appear in viral DNA preventing its replication in the cell |
| 3. | can cut the plasmid DNA of the bacterial cell that allows them to recombine foreign DNA into their plasmid DNA |
| 4. | help the bacterium take up foreign DNA from their environment and combine it into their genome |
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