Which of the following factors is responsible for the formation of concentrated urine?
1. | Hydrostatic pressure during glomerular filtration. |
2. | Low levels of antidiuretic hormone. |
3. | Maintaining hyperosmolarity towards inner medullary interstitium in the kidneys. |
4. | Secretion of erythropoietin by Juxtaglomerular complex. |
The increase in osmolarity from outer to inner medullary interstitium is maintained due to :
(i) Close proximity between Henle's loop and vasa recta
(ii) Counter current mechanism
(iii) Selective secretion of HCO3¯ and hydrogen ions in PCT
(iv) Higher blood pressure in glomerular capillaries
(1) Only(ii)
(2) (iii) and (iv)
(3) (i), (ii) and (iii)
(4) (i) and (ii)