The number of genes in human genome is found to be much less than what was initially expected as humans are capable of making large number of diverse proteins. This paradox can be best explained by:
1. Gene editing
2. Alternative splicing
3. Intron excision
4. Post transcriptional modification
In sea urchin DNA, which is double stranded, 17% of the bases were shown to be cytosine. The percentages of the other three bases expected to be present in this DNA are :
1. G 17%, A 16.5%,T32.5%
2. G 17%, A 33%,T 33%
3. G8.5%,A50%, T24.5%
4. G 34%,A 24.5%,T 24.5%
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Let us presume that it is possible to view enzymes and organelles in a cell, including those involved with gene expression. A prokaryotic cell can be differentiated from a eukaryotic cell because it can be seen that:
1. the nucleotides in the promoter are different in prokaryotes and eukaryotes.
2. the actual genes are more widely-spaced apart in eukaryotes than prokaryotes.
3. ribosomes have started translating mRNA that was still being synthesized by RNA polymerase.
4. prokaryotic mRNA does not contain introns.
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The human chromosome with the highest and least number of genes in them are respectively:
1. Chromosome 21 and Y
2. Chromosome 1 and X
3. Chromosome 1 and Y
4. Chromosome X and Y
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Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNA?
1. Rosalind Franklin
2. Maurice Wilkins
3. Erwin Chargaff
4. Meselson and Stahl
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DNA is a polymer of nucleotides which are linked to each other by 3’-5’ phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
1. Replace purine with pyrimidines
2. Remove/Replace 3' OH group in deoxy ribose
3. Remove/Replace 2' OH group with some other group in deoxy ribose
4. Both ‘b’ and ‘c’
A mutation at a gene locus changes a character due to change in
1. DNA replication
2. Protein synthesis pattern
3. RNA transcription pattern
4. Protein structure
Degeneration of genetic code is due to
1. First member of codons
2. Second member of codons
3. Third member of codons
4. Entire codons.
In gene mutation, adenine is replaced by guanine. It is
1. Frame-shift mutation
2. Transcription
3. Transition
4. Transversion
In bacterial DNA replication, synthesis starting from the site of origin of replication
1. Involves RNA primers
2. Requires telomerase
3. Proceeds unidirectionally
4. Moves bidirectionally