Q. No.The backbone of a polynucleotide chain is made of:
| 1. | Sugar and nitrogenous bases |
| 2. | Phosphate and nitrogenous bases |
| 3. | Sugar and phosphate |
| 4. | Sugar, phosphate, and nitrogenous bases |
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Watson and Crick based their model of DNA on X-ray diffraction data produced by:
| 1. | Hershey and Chase | 2. | Marie Curie and Pierre Curie |
| 3. | Franklin and Wilkins | 4. | Meselson and Stahl |
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According to Erwin Chargaff, in a double-stranded DNA
| 1. | The ratios between Adenine and Thymine, and, Guanine and Cytosine are constant and equal. |
| 2. | The ratios between Adenine and Thymine, and, Guanine and Cytosine are constant but are not equal to one. |
| 3. | The ratios between Adenine and Guanine, and, Thymine and Cytosine are constant and equal. |
| 4. | The ratios between Adenine and Guanine, and, Thymine and Cytosine are constant but are not equal to one. |
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The base pairing in a double stranded DNA is correctly described as:
| 1. | Similar | 2. | Identical |
| 3. | Complementary | 4. | Synergistic |
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If each strand of a dsDNA acts as a template for a new strand, the two daughter DNAs will be:
| 1. | Complementary to each other |
| 2. | Identical to the parental DNA |
| 3. | Similar to each other |
| 4. | Complementary to the parental DNA |
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Which of the following is not a feature of the double helix model of DNA?
| 1. | The two chains have anti-parallel polarity |
| 2. | A purine always comes opposite to a pyrimidine |
| 3. | The pitch of the DNA is 3.4 nm |
| 4. | The two chains are coiled in a left handed fashion |
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| Statement I: | A shows the hydrogen bonds where a triple bond links Guanine and Cytosine and a double bond links Adenine and Thymine. |
| Statement II: | If Adenine in such a dsDNA molecule is found to be 20 %, the amount of Cytosine in this ds DNA molecule is expected to be 20 %. |
1. Statement I is correct, Statement II is incorrect
2. Statement I is incorrect, Statement II is correct
3. Statement I is incorrect, Statement II is incorrect
4. Statement I is correct, Statement II is correct
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| I. | A represents a base pair where the plane of one base pair stacks over the other in the double helix giving the helix more stability in addition to hydrogen bonds. |
| II. | There are 10 base pairs in one complete turn of B-dNA. |
| III. | B is the backbone constituted by sugar-phosphate. |
| IV. | The two strands are parallel-oriented in the same direction with respect to each other. |
| V: | The diameter is uniform, around 2.0nm. |
| 1. | Only I, II, and III | 2. | Only II, III, IV, and V |
| 3. | Only I, II, III, and V | 4. | I, II, III, IV and V |
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The distance between a base pair in the DNA double helix is approximately:
| 1. | 2.0 nm | 2. | 0.34 nm |
| 3. | 20 nm | 4. | 3.4 nm |
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