Consider the following diagram showing the working of the lac operon in E.coli in the presence of an inducer and choose the correct statement from the ones given below:
  

1. A is the inducer and can be either lactose or cAMP.
2. B is the enzyme that will metabolize glucose, the preferred energy source.
3. Some amount of C will be present in the cell even if lactose is absent.
4. The absence of D will stop lactose from entering the cell.

Subtopic:  Gene Regulation: Lac Operon |
 54%
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Study the diagram given below and choose the correct information that can be deduced:
   

1. The core RNA polymerase is capable of catalyzing elongation only.
2. Sigma factor and Rho factor are needed for the termination of transcription.
3. DNA Helicase opens the strand of the DNA.
4. Both strands of DNA are transcribed by the same RNA polymerase.

Subtopic:  Transcription: I |
 63%
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Consider the transcription unit given in the following diagram and choose the correct statements:
  

I: The promoter on the template is situated upstream and 5’ to the structural gene.
II: It is the presence of the structural gene that defines the template strand.
III: The coding strand does not code for anything and is displaced during transcription.
 
1. I and II only 2. I and III only
3. II and III only 4. I, II and III
Subtopic:  Transcription |
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Consider the following statements:

I. Deoxyribonucleoside triphosphates act as substrates as well as provide energy for polymerization reaction during DNA replication.
II. The replication of DNA is both semiconservative and semi-discontinuous
III. In bacterial DNA replication, there are multiple ori and replication fork moving bi-directionally

Which of the above statements are true?

1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  DNA Replication: I | DNA Replication: II | DNA Replication |
 57%
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Which of the following cannot be inferred from the information given in the following diagram?
 

1. The DNA from the crime scene matches that of individual B
2. VNTRs are hypervariable
3. The larger fragments remain near the point of introduction in the gel electrophoresis
4. The smaller chromosomes in the human genome have smaller repeats of VNTR
Subtopic:  DNA Fingerprinting |
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Consider the following statements:

I: In prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression.
II: Regulation of lac operon by CAP is referred to as negative regulation.
III: The inducer of the lac operon is lactose.

Which of the above statements are true?

1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  Gene Regulation: Lac Operon |
 56%
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Consider the following statements:

I: All the reference point while defining a transcription unit is made with the coding strand.
II: It is the presence of a promoter in a transcription unit that also defines the template and coding strands.
III: Exons are said to be sequences that do not appear in mature or processed RNA.

Which of the above statements are true?

1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  Transcription |
 79%
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Consider the following statements:

I: RNA is the genetic material of the QB bacteriophage.
II: DNA chemically is less reactive and more stable than RNA.
III: Viruses having RNA genomes and shorter life spans mutate & evolve slowly.

Which of the above statements are true?

1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  DNA vs RNA as Genetic Material |
 73%
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Consider the following statements:

I: The largest known human gene is dystrophin at 2.4 million bases.
II: Repeated sequences make up a very large portion of the human genome.
III: There are about 2.4 million locations where single-base DNA differences occur in humans.

Which of the above statements are true?

1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  Human Genome Project |
 70%
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The DNA profiles below represent four different individuals. Which of the following statements is consistent with the results?

    
1. B is the child of A and C.
2. C is the child of A and B.
3. D is the child of B and C.
4. A is the child of B and C.

Subtopic:  DNA Fingerprinting |
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