Identify the correct statements:
 
I: It is the metabolic, physiological, or environmental conditions that regulate the expression of genes. 
II: The development and differentiation of embryos into adult organisms are also a result of the coordinated regulation of the expression of several sets of genes.
  
1.Only I2.Only II
3.Both I and II4.Neither I nor II

Subtopic:  Gene Regulation: Introduction | Gene Regulation in Eukaryotes |
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): In a transcription unit, the activity of RNA polymerase at a given promoter is in turn regulated by interaction with accessory proteins. 
Reason (R): These regulatory proteins can act both positively (activators) and negatively (repressors). 
In the light of the above statements, choose the most appropriate answer from the options given below :
1. Both (A) and (R) are true but (R) is not the correct explanation of (A).
2. Both (A) and (R) are false.
3. Both (A) and (R) are true and (R) is the correct explanation of (A).
4. (A) is true but (R) is false.
Subtopic:  Gene Regulation: Lac Operon | Gene Regulation in Eukaryotes |
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Identify the incorrect statement:
 
I: The operator region is adjacent to the promoter elements in most operons and in most cases the sequences of the operator bind a repressor protein. 
II: Each operon has its specific operator and specific repressor. 
 
1. Only I 2. Only II
3. Both I and II 4. Neither I nor II
Subtopic:  Gene Regulation: Lac Operon |
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): Lactose is the inducer of the lac operon in E.coli.
Reason (R): Lactose is the inhibitor of the lac operon.
In the light of the above statements, choose the most appropriate answer from the options given below :
1. Both (A) and (R) are True and (R) is the correct explanation of (A).
2. Both (A) and (R) are False.
3. Both (A) and (R) are True but (R) is not the correct explanation of (A).
4. (A) is True but (R) is False.
Subtopic:  Gene Regulation: Lac Operon |
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Study the diagram of the lac operon given below and select the correct statements:

   
 
Statement I: This is the working of a lac operon in the absence of an inducer.
Statement II: Repressor binds to the operator region and allows RNA polymerase to transcribe the operon.

1. Only Statement I 
2. Only Statement II 
3. Both Statement I and Statement II 
4. Neither Statement I nor Statement II 
Subtopic:  Gene Regulation: Lac Operon |
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): Regulation of lac operon by a repressor is referred to as negative regulation.
Reason (R): lac operon is under the control of positive regulation as well.
In the light of the above statements, choose the most appropriate answer from the options given below :
1. Both (A) and (R) are true but (R) is not the correct explanation of (A).
2. Both (A) and (R) are false.
3. Both (A) and (R) are true and (R) is the correct explanation of (A).
4. (A) is true but (R) is false.
Subtopic:  Gene Regulation: Lac Operon |
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): Human Genome Project was closely associated with the rapid development of a new area in biology called Bioinformatics.
Reason (R): One of the greatest impacts of having the Human Genome sequence may well be enabling a radically new approach to biological research.
In the light of the above statements, choose the most appropriate answer from the options given below :
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. Both (A) and (R) are false.
4. (A) is true but (R) is false.
Subtopic:  Human Genome Project |
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): Learning about non-human organisms DNA sequences is not important for human beings.
Reason (R): The Genetic code is not universal.
In the light of the above statements, choose the most appropriate answer from the options given below :
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are false.
3. Both (A) and (R) are true but (R) is not the correct explanation of (A).
4. (A) is true but (R) is false.
Subtopic:  Human Genome Project | Genetic Code |
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The goals of the Human Genome Project include all the following except:
 
1. Identify all the approximately 20,000-25,000 genes in human DNA and determine the sequences of the 3 billion chemical base pairs that make up human DNA.
2. Store the information in databases, improve tools for data analysis, and transfer related technologies to other sectors, such as industries.
3. Address the ethical, legal, and social issues (ELSI) that may arise from the project.
4. Develop technology to enable the introduction of genes into humans to manipulate their phenotypes and allow humans to demand a tailor-made gene composition for themselves.
Subtopic:  Human Genome Project |
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Which fact regarding the Human Genome Project is not correct?
1. The Human Genome Project was a 13-year project coordinated by the U.S. Department of Energy and the National Institute of Health.
2. Many non-human model organisms, such as bacteria, yeast, Caenorhabditis Elegans (a free-living non-pathogenic nematode), Drosophila (the fruit fly), plants (rice and Arabidopsis), etc., have also been sequenced.
3. The sequence of chromosome 1 was completed only in May 2016 (this was the last of the 24 human chromosomes – 22 autosomes and X and Y – to be sequenced).
4. The fragments were sequenced using automated DNA sequencers that worked on the principle of a method developed by Frederick Sanger.
Subtopic:  Human Genome Project |
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