Q. No.Although gene expression in eukaryotes can take place at multiple levels. The most common level of gene expression would be:
1.
transcriptional level (formation of the primary transcript)
2.
processing level (regulation of splicing)
3.
transport of mRNA from the nucleus to the cytoplasm
4.
translational level
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| I: | It is the metabolic, physiological, or environmental conditions that regulate the expression of genes. |
| II: | The development and differentiation of embryos into adult organisms are also a result of the coordinated regulation of the expression of several sets of genes. |
| 1. | Only I | 2. | Only II |
| 3. | Both I and II | 4. | Neither I nor II |
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| Assertion (A): | In a transcription unit, the activity of RNA polymerase at a given promoter is in turn regulated by interaction with accessory proteins. |
| Reason (R): | These regulatory proteins can act both positively (activators) and negatively (repressors). |
| 1. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 2. | Both (A) and (R) are false. |
| 3. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 4. | (A) is true but (R) is false. |
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| I: | The operator region is adjacent to the promoter elements in most operons and in most cases the sequences of the operator bind a repressor protein. |
| II: | Each operon has its specific operator and specific repressor. |
| 1. | Only I | 2. | Only II |
| 3. | Both I and II | 4. | Neither I nor II |
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| Assertion (A): | Lactose is the inducer of the lac operon in E.coli. |
| Reason (R): | Lactose is the inhibitor of the lac operon. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are False. |
| 3. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 4. | (A) is True but (R) is False. |
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| Statement I: | This is the working of a lac operon in the absence of an inducer. |
| Statement II: | Repressor binds to the operator region and allows RNA polymerase to transcribe the operon. |
1. Only Statement I
2. Only Statement II
3. Both Statement I and Statement II
4. Neither Statement I nor Statement II
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| Assertion (A): | Regulation of lac operon by a repressor is referred to as negative regulation. |
| Reason (R): | lac operon is under the control of positive regulation as well. |
| 1. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 2. | Both (A) and (R) are false. |
| 3. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 4. | (A) is true but (R) is false. |
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| Assertion (A): | Human Genome Project was closely associated with the rapid development of a new area in biology called Bioinformatics. |
| Reason (R): | One of the greatest impacts of having the Human Genome sequence may well be enabling a radically new approach to biological research. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | Both (A) and (R) are false. |
| 4. | (A) is true but (R) is false. |
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| Assertion (A): | Learning about non-human organisms DNA sequences is not important for human beings. |
| Reason (R): | The Genetic code is not universal. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are false. |
| 3. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 4. | (A) is true but (R) is false. |
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| 1. | Identify all the approximately 20,000-25,000 genes in human DNA and determine the sequences of the 3 billion chemical base pairs that make up human DNA. |
| 2. | Store the information in databases, improve tools for data analysis, and transfer related technologies to other sectors, such as industries. |
| 3. | Address the ethical, legal, and social issues (ELSI) that may arise from the project. |
| 4. | Develop technology to enable the introduction of genes into humans to manipulate their phenotypes and allow humans to demand a tailor-made gene composition for themselves. |
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