Q. No.The chain termination method using Dideoxyribonucleoside triphosphates was given by:
1. Paul Berg 2. Fred Sanger 3. Marshall Nirenberg 4. George Gamow
A tract of repetitive DNA in which certain DNA motifs (ranging in length from 10–60 base pairs) are typically repeated 5-50 times is called:
| 1. | Satellite chromosome | 2. | Satellite DNA |
| 3. | Minisatellite | 4. | Microsatellite |
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Which of the following is not a salient feature of the human genome?
| 1. | The actual total number of genes is much higher than what was previously estimated. |
| 2. | Less than 2 percent of the genome codes for proteins. |
| 3. | The functions are unknown for over 50 percent of the discovered genes. |
| 4. | Repeated sequences make up a very large portion of the human genome. |
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What catalyzes the peptide bond formation in prokaryotes?
1. Proteases
2. A ribozyme
3. Sigma subunit of RNA polymerase
4. Rho factor proteins
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The template strand of a DNA molecule is 3’ – TAC – 5’. Which of the following anticodons of the tRNA molecule will hybridize with the codon of mRNA coded by this template?
| 1. | 3’ – TAC – 5’ | 2. | 5’ – AUG – 3’ |
| 3. | 5’ – CAU – 3’ | 4. | 5’ – UAC – 3’ |
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The genetic material for the first life on the earth was probably:
| 1. | ds DNA | 2. | ss DNA |
| 3. | Protein | 4. | RNA |
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The unequivocal proof that DNA is the genetic material came from Hershey and Chase’s experiment using bacteriophages. Which of the following is consistent with the results?
| 1. | When bacteriophages radioactively labeled with 32P were allowed to infect bacteria, all the infected cells became radioactive and much of the radioactivity was passed on to the next generation of bacteriophages. |
| 2. | When bacteriophages radioactively labeled with 35S were allowed to infect bacteria, all the infected cells became radioactive and much of the radioactivity was passed on to the next generation of bacteriophages. |
| 3. | When bacteriophages radioactively labeled with 32P were allowed to infect bacteria, none of the infected cells became radioactive. |
| 4. | When bacteriophages radioactively labeled with 35S were allowed to infect bacteria, all infected cells became radioactive but no radioactivity was passed on to the next generation of bacteriophages. |
Identify the correct statements regarding salient features of the Double-helix structure of DNA:
| I: | Backbone is constituted by nitrogenous bases. |
| II: | The two chains have anti-parallel polarity. |
| III. | There is complementary base pairing between nitrogenous bases. |
| IV. | The two chains are coiled in a left-handed fashion. |
| V. | The plane of one base pair stacks over the other. |
| 1. | All except I | 2. | All except I and IV |
| 3. | Only II and III | 4. | Only III |
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Nucleic acid synthesis in a cell is blocked. The first affected molecular process will most likely be:
| 1. | mRNA synthesis | 2. | DNA replication |
| 3. | Translation | 4. | hnRNA splicing |
The salient features of the Double-helix structure of DNA include all except:
| 1. | The two chains are anti-parallel |
| 2. | Complementary base pairing results in a uniform diameter of the helix |
| 3. | The two chains are coiled in a left-handed fashion |
| 4. | The pitch of the helix is 3.4 nm |
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