Which of the following statements is correct about the role of regulatory proteins in transcription in prokaryotes?

1. They only increase the expression
2. They only decrease the expression
3. They interact with RNA polymerase but do not affect the expression
4. They can act both as activators and as repressors

Subtopic:  Gene Regulation: Lac Operon |
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While analysing the DNA of an organism a total number of 5386 nucleotides were found out of which the proportion of different bases were: Adenine = 29%, Guanine = 17%, Cytosine = 32%, Thymine = 17%. Considering Chargaff’s rule it can be concluded that:

1. it is a double-stranded circular DNA
2. It is single-stranded DNA
3. It is a double-stranded linear DNA
4. No conclusion can be drawn
Subtopic:  The DNA | DNA Double Helix |
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DNA fingerprinting is related to:

1. Molecular analysis of profiles of DNA samples
2. Analysis of DNA samples using imprinting devices
3. Techniques used for molecular analysis of different specimens of DNA
4. Techniques used in the identification of fingerprints of different persons
Subtopic:  DNA Fingerprinting |
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What is it that forms the basis of DNA Fingerprinting?

1. The relative proportions of purines and pyrimidines in DNA.
2. The relative difference in the DNA occurrence in blood, skin, and saliva.
3. The relative amount of DNA in the ridges and grooves of the fingerprints.
4. Satellite DNA occurring as highly repeated short DNA segments
Subtopic:  DNA Fingerprinting |
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Select the correct option:

The direction of RNA synthesis

The direction of reading of the template DNA strand

1.

5' - 3'

3' - 5'

2.

3' - 5'

 5' - 3'

3.

 5' - 3'

5' - 3'

4.

3' - 5'

 3' - 5'

Subtopic:  Transcription |
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Which of the following is not required for any of the techniques of DNA fingerprinting available at present?   

1.DNA -DNA hybridization2.Polymerase chain reaction
3.Zinc finger analysis4.Restriction enzymes

Subtopic:  DNA Fingerprinting |
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Taylor conducted experiments to prove the semiconservative mode of chromosome replication on:     

1. E. coli 2. Vinca rosea
3. Vicia faba 4. Drosophila melanogaster
Subtopic:  Transcription |
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If there are 999 bases in RNA that code for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered?

1. 1 2. 11
3. 33 4. 333
Subtopic:  Transcription:II | Transcription |
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Identifying all the genes in the genome that are transcribed into RNA is called:

1.Expressed Sequence Tag2.Sequence Annotation
3.Inverse PCR4.Retrotransposition

Subtopic:  Human Genome Project |
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For the multiplication of any alien piece of DNA in an organism it needs to be a part of a chromosome that has a specific:
1. Telomeric sequence
2. Multiple cloning site
3. Ori
4. Selectable marker

Subtopic:  DNA Replication |
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