Which of the following meta-directing substituents is the most deactivating in aromatic substitution?

1. –SO3H 2. –COOH
3. –NO2 4. –C≡N
Subtopic:  Directive Effect of functional grp |
 68%
Level 2: 60%+
AIPMT - 2013
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Among cyclohexanol (I), acetic acid (II), 2, 4, 6-trinitrophenol (III) and phenol (IV) the correct order of decreasing acidic character will be:

1. III>II>IV>I 2. II>III>I>IV
3. II>III>IV>I 4. III>IV>II>I
Subtopic:  Directive Effect of functional grp |
 53%
Level 3: 35%-60%
AIPMT - 2010
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The relative reactivities of acyl compounds towards nucleophilic substitution are in the order of:

1. Acyl chloride > Acid anhydride > Ester > Amide

2. Ester > Acyl chloride > Amide >Acid anhydride

3. Acid anhydride > Amide > Ester > Acyl chloride

4. Acyl chloride > Ester > Acid anhydride > Amide

Subtopic:  Directive Effect of functional grp |
 61%
Level 2: 60%+
AIPMT - 2008
Hints

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Which one of the following is most reactive towards electrophilic attack?

1. 2.
3. 4.
Subtopic:  Directive Effect of functional grp |
 57%
Level 3: 35%-60%
AIPMT - 2008
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