Read the following statements and choose the set of correct statements: 
(a) Euchromatin is loosely packed chromatin
(b) Heterochromatin is transcriptionally active
(c) Histone octomer is wrapped by negatively charged DNA in nucleosome
(d) Histones are rich in lysine and arginine
(e) A typical nucleosome contains 400 bp of DNA helix

Choose the correct answer from the options given below
1. (a), (c), (e) only
2. (b), (d), (e) only
3. (a), (c), (d) only
4. (b), (e) only
Subtopic:  DNA Double Helix | DNA Packaging |
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The process of translation of mRNA to proteins begins as soon as
1. The tRNA is activated and the larger subunit of ribosome encounters mRNA
2. The small subunit of ribosome encounters mRNA
3. The larger subunit of ribosome encounters mRNA
4. Both the subunits join together to bind with mRNA

Subtopic:  Translation |
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DNA polymorphism forms the basis of
1. Translation
2. Genetic mapping
3. DNA finger printing
4. Both genetic mapping and DNA fingerprinting

Subtopic:  DNA Fingerprinting |
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If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different segments, the methodology adopted by him is called as:
1. Bioinformatics
2. Sequence annotation
3. Gene mapping
4. Expressed sequence tags

Subtopic:  Human Genome Project |

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In an E.coli strain i gene gets mutated and its product cannot bind the inducer molecule. If growth medium is provided with lactose, what will be the outcome ?
1. RNA polymerase will bind the promoter region 
2. Only z gene will get transcribed 
3. z, y, a genes will be transcribed 
4. z, y, a genes will not be translated 
Subtopic:  Gene Regulation: Lac Operon |
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If the length of a DNA molecules is 1.1 metres, what will be the approximate number of base pairs?
1. \(6.6 \times 10^{6} \mathrm{bp}\) 2. \(3.3 \times 10^{9} \mathrm{bp}\)
3. \(6.6 \times 10^{9} \mathrm{bp}\) 4. \(3.3 \times 10^{6} \mathrm{bp}\)
Subtopic:  The DNA |
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Ten E.coli cells with \({ }^{15} \mathrm{~N}\) - ds DNA are incubated in medium containing \({ }^{14} \mathrm{~N}\) nucleotide. After 60 minutes, how many E.coli cells will have DNA totally free from \({ }^{15} \mathrm{~N}\) ?
1. 80 cells
2. 20 cells
3.  40 cells
4. 60 cells
Subtopic:  Search for Genetic Material |
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Which one of the following is not a criterion of genetic material? 
1. Should not provide the scope for changes for evolution 
2. Should be able to express itself in the form of Mendelian character 
3. Should be able to generate its replica 
4. Should be stable chemically and structurally

Subtopic:  DNA vs RNA as Genetic Material |
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DNA replication is semi-conservative in nature was experimentally proved in eukaryotes by: 
1. Hershey and Chase 
2. Macleod and McCarty 
3. Meselson and Stahl 
4. Talyor and his colleagues 

Subtopic:  DNA Replication |
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Which one of the following experiments of Frederick Griffith resulted in the discovery of bacterial transformation? 
1. S-stain(heat-killed) → injected in to Mice  → Mice lived 
2. S-strain (heat killed) + R-strain(live)  →injected in to Mice  → Mice died 
3. S-stain  → injected in to Mice  → Mice died 
4. R-strain  → injected in to Mice  → Mice lived 

Subtopic:  Search for Genetic Material |
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