Which scientist experimentally proved that DNA is the sole genetic material in bacteriophage?

1. Beadle and Tatum

2. Messelson and Stahl

3. Hershey and Chase

4. Jacob and Monod

What initiation and termination factors are involved in transcription in prokaryotes?

1. $\mathrm{\sigma }$ $\mathrm{and}$ $\mathrm{\rho }$, respectively

2. $\mathrm{\alpha }$ $\mathrm{and}$ $\mathrm{\beta }$, respectively

3. $\mathrm{\beta }$ $\mathrm{and}$ $\mathrm{\gamma }$, respectively

4. $\mathrm{\alpha }$ $\mathrm{and}$ $\mathrm{\sigma }$, respectively

Amino acid sequence in protein synthesis is determined by sequence of  
1. rRNA
2. tRNA
3. mRNA
4. cDNA.

Read the following four statements (A-D):  
(A) In transcription, adenosine pairs with uracil.
(B) Regulation of lac operon by repressor is referred to as positive regulation.
(C) The human genome has approximately 50,000 genes.
(D) Haemophilia is a sex-linked recessive disease.
How many of the above statements are right ?
1. Two
2. Three
3. Four
4. One

Which enzyme/s will be produced in a cell in which there is a nonsense mutation in the lac Y gene?

1. Lactose permease

2. Transacetylase

3. Lactose permease and transacetylase

4. β-galactosidase

Restriction endonuclease generated DNA fragments
separated by gel electrophoresis and blot transferred
onto a membrane filter are probed with radioactive
DNA fragment. This procedure is called
1. Gene cloning
2. The southern blotting technique
3. Northern blotting
4. Western blotting

Production of a human protein in bacteria by genetic engineering is possible because
1. Bacterial cell can carry out the RNA splicing.
2. The mechanism of gene regulation is identical in humans and bacteria.
3. The human chromosome can replicate in bacterium cell.
4. The genetic code is universal

What will be the sequence of mRNA produced by the following stretch of DNA?

3' ATGCATGCATGCATG 5' TEMPLATE STRAND

5' TACGTACGTACGTAC 3' CODING STRAND

1. 3' AUGCAUGCAUGCAUG 5'

2. 5' UACGUACGUACGUAC 3'

3. 3' UACGUACGUACGUAC 5'

4. 5' AUGCAUGCAUGCAUG 3'

By performing a series of experiments that showed the effect of R and S strains of Streptococcus pneumoniae on mice, Griffith concluded that

1. Protein digesting enzyme does not affect
      transformation.

2. DNA is more stable genetic material than RNA.

3. DNA replication is semi conservative.

4. Non-virulent bacteria were tranformed by heat killed
     virulent bacteria.

Choose the correct statements –
I. Binding of mRNA to the ribosome is loose and reversible.
II. The ribosome, which is composed of tRNA and proteins, consists of a small and large subunit.
III. Each of the 20 amino acids has a minimum of one specific tRNA molecule.
IV. tRNA^MET binds to the first codon (AUG) – this is called the START codon.
V. The second tRNA binds to the second codon so that their attached monosaccharides are next to each other.
VI. The newly formed polypeptide may undergo post-transcriptional modification.

1. I, III and IV
2. II, IV, VI
3. II, V and VI
4. I, V, VI.