Q. No.The salient features of the human genome include all except:
1. About 1.4 million SNP locations
2. Functions known for less than 50% of the discovered genes
3. The actual number of genes and the initial estimates are remarkable similar
4. More than 98% of genome does not code for proteins
1. About 1.4 million SNP locations
2. Functions known for less than 50% of the discovered genes
3. The actual number of genes and the initial estimates are remarkable similar
4. More than 98% of genome does not code for proteins
Match the columns with respect to the process of translation:
| Column I | Column II | ||
| (a) | UTR | (i) | Catalyst |
| (b) | rRNA | (ii) | Template |
| (c) | mRNA | (iii) | Reads the genetic code |
| (d) | tRNA | (iv) | For efficiency |
| (a) | (b) | (c) | (d) | |
| 1. | (i) | (ii) | (iii) | (iv) |
| 2. | (iv) | (i) | (ii) | (iii) |
| 3. | (iv) | (iii) | (ii) | (i) |
| 4. | (ii) | (iii) | (iv) | (i) |
Consider the following statements regarding DNA fingerprinting:
i. The technique was initially developed by Alec Jeffreys.
ii. Hybridisation using labeled VNTR probe.
iii. Sensitivity of the technique has been increased by the use of PCR.
iv. Sequences used for DNA fingerprinting generally code for many proteins.
v. Monozygotic twins have identical DNA fingerprints.
1. All statements are correct
2. Only '4' is incorrect
3. 4 and 5 are incorrect
4. 1, 3, 4, and 5 are correct
Which of the following scientist is responsible for the synthesis of protein in a cell-free system?
1. Har Gobind Khorana
2. Marshall Nirenberg
3. Severo Ochoa
4. Frederic Sanger
Distribution of newly synthesized DNA in the chromosomes is by semi-conservative means is experimentally shown by Taylor et al by using
1. Radioactive adenosine
2. Radioactive thymidine
3. Radioactive guanosine
4. Radioactive cytidine
During DNA replication, two strands of DNA cannot be separated in their entire length in one step because?
1. Due to high energy requirement
2. Due to complementary base pairing
3. Due to antiparallel nature of DNA strand
4. Due to absence of enzyme DNA polymerase
In a transcription unit, with respect to structural gene, the promoter is located:
1. Upstream and 5’
2. Upstream and 3’
3. Downstream and 5’
4. Downstream and 3’
DNA replication is correctly described as:
1. Semi-conservative and Continuous
2. Semi-conservative and Discontinuous
3. Conservative and Continuous
4. Semi-conservative and Semi-discontinuous
The unequivocal proof that DNA is the genetic material was provided by:
1. Avery, Macleod and McCarty
2. Hershey and Chase
3. Meselson and Stahl
4. Watson and Crick
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