Q. No.Consider the following statements:
I.
Deoxyribonucleoside triphosphates act as substrates as well as provide energy for polymerization reaction during DNA replication.
II.
The replication of DNA is both semiconservative and semi-discontinuous
III.
In bacterial DNA replication, there are multiple ori and replication fork moving bi-directionally
Which of the above statements are true?
1.
I and II only
2.
I and III only
3.
II and III only
4.
I, II, and III
Which of the following was presented as evidence in favor of “the RNA world” hypothesis?
1. The fact that DNA can encode genetic information
2. The fact that enzymes, made of protein, can catalyze biological reactions
3. The discovery that some enzymes are composed of RNA rather than protein
4. The discovery of new life forms that encode their genetic information in RNA rather than DNA
Which of the following is not correct for “Snips”?
| 1. | There are 1.4 million locations in human genome. |
| 2. | Where single base differences occur. |
| 3. | They shed light on chromosome structure, dynamics and evolution. |
| 4. | It promises to revolutionise the processes of finding chromosomal locations for disease associated sequences. |
Study the results of the Meselson and Stahl experiment. What theoretically possible mode of DNA replication can be excluded after one round of replication?
| 1. | Conservative | 2. | Semiconservative |
| 3. | Disruptive | 4. | Both 1 and 3 |
Consider the transcription unit given in the following diagram and choose the correct statements:
| I: | The promoter on the template is situated upstream and 5’ to the structural gene. |
| II: | It is the presence of the structural gene that defines the template strand. |
| III: | The coding strand does not code for anything and is displaced during transcription. |
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II and III |
Study the diagram given below and choose the correct information that can be deduced:
| 1. | The core RNA polymerase is capable of catalyzing elongation only. |
| 2. | Sigma factor and Rho factor are needed for the termination of transcription. |
| 3. | DNA Helicase opens the strand of the DNA. |
| 4. | Both strands of DNA are transcribed by the same RNA polymerase. |
Which of the following cannot be inferred from the information given in the following diagram?
| 1. | The DNA from the crime scene matches that of individual B |
| 2. | VNTRs are hypervariable |
| 3. | The larger fragments remain near the point of introduction in the gel electrophoresis |
| 4. | The smaller chromosomes in the human genome have smaller repeats of VNTR |
Consider the following statements:
| I: | The cellular factory responsible for synthesizing proteins is the ribosome. |
| II: | The ribosome also acts as a catalyst for the formation of a peptide bond. |
| III: | The UTRs (untranslated regions) in an mRNA are not required for translation. |
Which of the above statements are true?
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
Consider the following statements:
| I: | In prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression. |
| II: | Regulation of lac operon by CAP is referred to as negative regulation. |
| III: | The inducer of the lac operon is lactose. |
Which of the above statements are true?
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
Consider the following statements:
| I: | The VNTRs belong to a class of satellite DNA called as mini-satellite. |
| II: | Southern blotting is the transfer of DNA fragments to a filter cellulose membrane. |
| III: | VNTRs are used in DNA fingerprinting as they do not show any variations and are not inherited. |
Which of the above statements are true?
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
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