The major approaches used in HGP for identifying genes were

(1) BLAST

(2) Expressed Sequence Tags

(3) Sequence annotation

(4) b and c

Which of the following were not used in HGP?

(1)Vectors like BAC and YAC

(2) Hosts like plants and animals

(3)Protein sequencers

(4)DNA sequencers

Frederick Sanger is credited for the invention of

(1)DNA sequencing method

(2)Protein sequencing method

(3)Both

(4)RNA sequencing method

The last chromosome to be sequenced in HGP was

(1) the last chromosome of the human genome

(2)the first chromosome of the human genome

(3)chromosome I

(4)Both b and c

The number of autosomal chromosomes in the human beings are

(1) 44

(2) 22

(3) 2

(4) 1

How many of the following were the features of the Human Genome

1. 99.9% bases are present are exactly same in all humans

2. all sequences were found to be coding sequences

3. Repeated sequences make up very large portion of the human genome

4. Repeated sequences are useful for chromosome structure, dynamics and evolution

5. The maximum no of genes were found to be present at the chromosome which was last sequenced

6. The fewest no of genes were found to be present at the chromosome which is present in male only.

(1) 1

(2) 2

(3) 3

(4) 5

The largest known human gene is

(1) Dystrophin protein gene on X chromosome

(2) Sry gene on Y chromosome

(3) Dystropin protein gene on Y chromosome

(4) Sry gene on X chromosome

Isotopes used in proving semiconservative replication of DNA were:

(1) ¹⁴N ¹⁴C            

(2) ¹⁴N ¹⁵N            

(3) ¹⁴N ³¹P             

(4) ¹⁴C ³¹P

Column-I                                               Column-II
I. Genome of ϕ 174 bacteriophage           A. Ribozyme, RNAase
II. Purine                                               B. 5386 Nucleotides
III. Catalytic RNA                                   C. Adenine and Guanine
IV. Any chemical change in DNA              D. Mutation
The correct match is:
(1) I - D, II - B, III - A, IV - C                 

(2) I - B, II - A, III - D, IV - C

(3) I - D, II - C, III - A, IV - B                 

(4) I - B, II - C, III - A, IV - D

Column-I                                        Column-II
I. Operator site                               A. Binding site for RNA polymerase
II. Promoter site                              B. Binding site for repressor molecule
III. Structural gene                          C. Codes for enzyme protein
IV. Regulator gene                          D. Code for repressor molecules
The correct match is:
(1) I - B, II - A, III - C, IV - D         

(2) I - B, II - A, III - D, IV - C

(3) I - D, II - C, III - A, IV - B         

(4) I - B, II - C, III - A, IV - D