Q. No.Distribution of newly synthesized DNA in the chromosomes is by semi-conservative means is experimentally shown by Taylor et al by using
1. Radioactive adenosine
2. Radioactive thymidine
3. Radioactive guanosine
4. Radioactive cytidine
During DNA replication, two strands of DNA cannot be separated in their entire length in one step because?
1. Due to high energy requirement
2. Due to complementary base pairing
3. Due to antiparallel nature of DNA strand
4. Due to absence of enzyme DNA polymerase
Which among the following characteristics confers
stability to the DNA helical structure?
i. Presence of Uracil.
ii. Plane of one base pair stacking over the other in
DNA helix.
iii. Left handed fashion coiling of DNA helix.
iv. Presence of hydrogen bonds.
1. i and ii
2. ii and iii
3. iii and iv
4. ii and iv
What is/are the role(s) of deoxyribonucleoside
triphosphates during DNA replication?
A. Act as substrate.
B. Catalyse the polymerisation of ribonucleic acid.
C. Provide energy for polymerisation reaction.
1. A only
2. B only
3. A and B
4. A and C
The following diagram refers to the process of transcription in Eukaryotes. Identify A, B, C and D –
| 1. | A – RNA polymerase II, B – Exon, C – Intron, D – Poly A tail |
| 2. | A – DNA polymerase II, B – Intron, C – Exon, D – Poly A tall |
| 3. | A – RNA polymerase II, B – Intron, C – Exon, D – Poly A tail |
| 4. | A – RNA polymerase II, B – Intron, C – Exon, D – Poly G tail |
Choose the correct statements –
I. Binding of mRNA to the ribosome is loose and reversible.
II. The ribosome, which is composed of tRNA and proteins, consists of a small and large subunit.
III. Each of the 20 amino acids has a minimum of one specific tRNA molecule.
IV. tRNAMET binds to the first codon (AUG) – this is called the START codon.
V. The second tRNA binds to the second codon so that their attached monosaccharides are next to each other.
VI. The newly formed polypeptide may undergo post-transcriptional modification.
1. I, III and IV
2. II, IV, VI
3. II, V and VI
4. I, V, VI.
Which of the following scientist is responsible for the synthesis of protein in a cell-free system?
1. Har Gobind Khorana
2. Marshall Nirenberg
3. Severo Ochoa
4. Frederic Sanger
Consider the following statements regarding DNA fingerprinting:
i. The technique was initially developed by Alec Jeffreys.
ii. Hybridisation using labeled VNTR probe.
iii. Sensitivity of the technique has been increased by the use of PCR.
iv. Sequences used for DNA fingerprinting generally code for many proteins.
v. Monozygotic twins have identical DNA fingerprints.
1. All statements are correct
2. Only '4' is incorrect
3. 4 and 5 are incorrect
4. 1, 3, 4, and 5 are correct
Match the columns with respect to the process of translation:
| Column I | Column II | ||
| (a) | UTR | (i) | Catalyst |
| (b) | rRNA | (ii) | Template |
| (c) | mRNA | (iii) | Reads the genetic code |
| (d) | tRNA | (iv) | For efficiency |
| (a) | (b) | (c) | (d) | |
| 1. | (i) | (ii) | (iii) | (iv) |
| 2. | (iv) | (i) | (ii) | (iii) |
| 3. | (iv) | (iii) | (ii) | (i) |
| 4. | (ii) | (iii) | (iv) | (i) |
By performing a series of experiments that showed the effect of R and S strains of Streptococcus pneumoniae on mice, Griffith concluded that
1. Protein digesting enzyme does not affect
transformation.
2. DNA is more stable genetic material than RNA.
3. DNA replication is semi conservative.
4. Non-virulent bacteria were tranformed by heat killed
virulent bacteria.
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