NEET Zoology Biotechnology Principles and Processes Questions Solved

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Why is it not possible for an alien DNA to become part of a chromosome anywhere along its length and replicate normally?                                                                                                                  (1) 

Replication starts from a specific sequence of DNA known as origin of replication (ori). If any piece of DNA is linked to this sequence it can be made to replicate within the host cells. Alien DNA requries this specific sequence to replicate. As this site may not be present in all alien DNA, so it cannot replicate normally by attaching to the chromosome.                                                                              (1) 

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