NEET Botany Molecular Basis of Inheritance Questions Solved


(i) Name the scientist who suggested that the genetic code should be made of a combination of three nucleotides.

(ii) Explain the basis on which he arrived at this conclusion.

(i) George Gamow 

(ii) According to him since there are only 4 bases and if they have to code for 20 amino acids, the code should constitute a combination of bases. If one nucleotide codes for one amino acid, then only four amino acids are formed. If two nucletides code for 2 amino acids then only 16 amino acids are formed. He suggested if three nucleotides code for one amino acid then it could code for all the 20 amino acids. His proposition was quite bold because, if a permutational combination of 434×4×4 would generate 64 codons, generating many more codons than required.

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