Transition state structure of the substrate formed during an enzymatic reaction is:
(a) Transient but stable (b) Permanent but unstable
(c) Transient and unstable (d) Permanent and stable
Each enzyme (E) has a substrate (S) binding site in its molecule so that a highly reactive enzyme-substrate complex (ES) is produced. This complex is short-lived and dissociates into its product(s) P and the unchanged enzyme with an intermediate formation of the enzyme-product complex (EP).