Adenosine deaminase (ADA deficiency) could be permanently cure, if the gene isolated from marrow cells producing ADA is introduced into cell at

(1) early embryonic stages

(2) Late embryonic stages

(3) early childhood

(4) None of the above

Subtopic:  Gene Therapy |
 96%
From NCERT
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The first clinical gene therapy was given for treating

(1) diabetes mellitus

(2) chickenpox

(3) rheumatoid arthritis

(4) adenosine deaminase deficiency

Subtopic:  Gene Therapy |
 95%
From NCERT
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The protein products of the following Bt toxin genes cry I Ac and cry II Ab are responsible for controlling

(1) bollworm

(2) roundworm

(3) moth

(4) fruit fly

Subtopic:  Bt Crops |
 95%
From NCERT
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Three critical research areas of biotechnology are:

I. Providing the best catalyst in the form of improved organism usually a microbe or pure enzyme

II. Multiple Ovulation Transfer Technology (MOET)

III. Creating optimal conditions through engineering for a catalyst to act.

IV. Downstream processing technologies

(1) I, II, III, IV      

(2) I, III, IV          

(3) I, II                 

(4) II and IV

Subtopic:  Intro to Agri Applications |
 78%
From NCERT
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Bt toxin is: 

(1) Intracellular lipids                      

(2) Intracellular crystalline protein

(3) Extracellular crystalline protein    

(4) Intracellular polysaccharide

Subtopic:  Bt Crops |
 84%
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Bt toxin is harmful to insects like:

(1) Lepidoterans (tobacco budworm, armyworms)

(2) Coleopterans (beetles)

(3) Dipterans (flies and mosquito)

(4) All are correct

Subtopic:  Bt Crops |
 95%
From NCERT
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Antisense RNA is:

(1) RNA that makes opposite sense

(2) RNA that investigators find confusing

(3) The non-coding strand of DNA molecule

(4) RNA that is complementary to certain mRNA

Subtopic:  Interference RNA Tech |
 73%
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Which of the following statements is false?

I. Insulin was originally extracted from pancreas of slaughtered pigs and cattle
II. Animal insulin is difficult to obtain
III. Animal insulin is identical to human insulin
IV. Non-human insulin caused some patients to develop allergy
V. Recombinant DNA allowed scientists to insert a human insulin gene into a bacterial expression vector
VI. Recombinant insulin is actually obtained from E. coli bacterial cell

1. Only I and II

2. Only III and IV

3. Only III

4. Only VI

Subtopic:  Med Applications & Humulin |
 63%
From NCERT
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Which step proved to be the main challenging obstacle in the production of human insulin by genetic engineering? 

(1) Splitting A and B polypeptide chains

(2) Addition of C-peptide to pro-insulin

(3) Getting insulin assembled into mature form

(4) Removal of C-peptide from active insulin

Subtopic:  Med Applications & Humulin |
 64%
From NCERT
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Which technique would you expect to be completely curative in SCID?

(1) Gene therapy in adult stage

(2) Gene therapy in embryonic stage

(3) Bone marrow transplantation

(4) Enzyme replacement therapy

Subtopic:  Gene Therapy |
 89%
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