What would happen, if in a gene encoding a polypeptide of 50 amino acids, 25th codon UAU is mutated to UAA? 
1. Two polypeptides of 24 and 25 amino acids will be formed 
2. A polypeptide of 25 amino acids will be formed 
3. A polypeptide of 49 amino acids will be formed 
4. A polypeptide of 24 amino acids will be formed 

Subtopic:  Translation |
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Which of the following is the sequence of mRNA transcribed from the below DNA? 
3' - ATCCCAGGTACCAT - 5' 
1. 3' - UAGGGUCCAUGGUA - 5' 
2. 5' - UAGGGUCCAUGGUA - 3' 
4. 3' -TAGGGTCCATGGTA -5' 
4. 5' - TAGGGTCCATGGTA - 3'
Subtopic:  Transcription |
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Process of transcription in bacteria involves 
1. Polyadenylation, initiation, termination 
2. Capping, elongation, termination 
3. Elongation, splicing, termination 
4. Initiation, elongation, termination 
Subtopic:  Transcription |
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During replication in E.coli, mutations inactivate the gene coding for beta-galactosidase. Which of the following will be affected? 
1. Hydrolysis of glucose 
2. Hydrolysis of lactose 
3. Hydrolysis of galactose 
4. Hydrolysis of xylulose 
Subtopic:  Gene Regulation: Lac Operon |
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In the genome, genes regulated by common regulator are placed together in an arrangement known as 
1. DNA 
2. Operon 
3. Spacer 
4. Repeat 
Subtopic:  Gene Regulation: Lac Operon |
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Match List I with List II
List I List II
A. Frederick Griffith I. DNA replicate semi-conservatively
B. Alfred Hershey & Martha chase II. Cell-free system for protein synthesis
C. Matthew Meselson & Frank Stahl III. Transforming principle
D. Marshall Nirenberg IV. DNA-Genetic material
Choose the correct answer from the following given below:
1. A-III     B-IV      C-I       D-II
2. A-I       B-II       C-III     D-IV
3. A-II      B-III      C-IV     D-I
4. A-IV     B-III      C-I       D-II
Subtopic:  DNA Replication | Search for Genetic Material |
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Given below are two statements
I: The process of transcription in eukaryotes with additional complexities -There are at least three RNA polymerases in the nucleus with clear cut division of labor. The RNA polymerase I transcribes rRNAs whereas the RNA polymerase III is responsible for transcription of tRNA, 5S rRNA and snRNAs. The RNA polymerase II transcribes precursor of mRNA and hnRNA.
II: The primary transcripts contain both the exons and introns are non-functional. It is subjected to a process of splicing whereas the introns are removed and exons are joined in a defined order. hnRNA undergoes additional processing called as capping and tailing.
In light of the above statements, choose the most appropriate answer from the options given below
1. Both statement I and statement II are true
2. Both statement I and statement II are false
3. Statement I is true but statement II is false
4. Statement I is false but statement II is true
Subtopic:  Transcription |
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In lac operon, operator sequence/region binds with
1. Regulatory gene to switch off the operon
2. Repressor protein to switch on the structural genes
3. Repressor protein to switch off the structural genes
4. Inducer to switch on the operon
Subtopic:  Gene Regulation: Lac Operon |
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Arrange in the correct sequence.
A. Isolation of DNA
B. Hybridisation using labeled VNTR probe
C. Digestion of DNA by restriction endonucleases
D. Separation of DNA fragments by electrophoresis
E. Blotting of separated DNA fragmented to synthetic membranes
Choose the correct answer from the options given below
1. A → E → B → C → D
2. A → C → E → B → D
3. A → C → D → E → B
4. A → D → C → B → E
Subtopic:  DNA Fingerprinting |
 84%
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The salient features of genetic code are
A. The codon is triplet, 61 codons for amino acids & 3 codons do not code for any amino acid, they function as stop codon
B. The codon is read in mRNA in contiguous fashion, no punctuations
C. UAA, UAG, UGA are stop terminator codons
D. Some codes are universal
E. AUG has dual function, it codes for phenylalanine (Phe) and it also acts as terminate the process 

Choose the correct answer from the options given below:
1. A, B, D only
2. A, B, C only
3. A, B, D, E oly
4. A & E only
Subtopic:  Genetic Code |
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