Cystic fibrosis affects the lungs, the pancreas, the digestive system, and other organs, resulting in symptoms ranging from breathing difficulties to recurrent infections. Which of the following terms best describes this?
1. incomplete dominance
2. multiple alleles

3.  pleiotropy
4. epistasis

 

Subtopic:  Polygenic Inheritance & Pleiotropy | Mendelian Disorders |
 80%
Level 1: 80%+
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How would one explain a test cross involving F1 dihybrid flies in which more parental-type offspring than recombinant-type offspring are produced?
1. The two genes are closely linked on the same chromosome
2. The two genes are linked but on different chromosomes
3. Recombination did not occur in the cell during meiosis
4. The test cross was improperly performed
Subtopic:  Understanding Linkage | Linkage Types | Recombination & Gene Mapping |
 84%
Level 1: 80%+
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In a linear chromosome map distances between four loci are -a and b = 20 mu; a and d = 6mu; b and c=8 mu; a and c= 12 mu. What will be the crossover frequency between c and d ? 
1. 12% 
2. 20% 
3. 3% 
4. 6%
Subtopic:  Chromosomal Basis of Inheritance: Introduction | Linkage Types | Recombination & Gene Mapping |
 63%
Level 2: 60%+
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Which of the following display female heterogametry? 
1. Drosophila melanogaster 
2. Apis mellifera 
3. Gallus gallus domesticus 
4. Periplaneta Americana 
Subtopic:  Sex Determination | Sex Determination: Further Considerations |
 57%
Level 3: 35%-60%
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In a particular chromosome, the recombination frequency between genes a &c is 5%; b & c is 15%; b &d is 9%; a &b is 20%; c &d is 24% and a & d is 29%. The sequence of genes in a chromosome is 
1. a, d, b, c 
2. d, b, a, c 
3. a, b, c, d 
4. a, c, b, d 
Subtopic:  Chromosomal Basis of Inheritance: Introduction | Recombination & Gene Mapping |
 72%
Level 2: 60%+
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Match List I with List II
                       
List I     List II
A. Mendelian Disorder  I. Chromosomal Theory of inheritance
B. Alfred Sturtevant II. Klinefelter's syndrome
C. Chromosomal Disorder III. Cystic fibrosis
D. Sutton and Boveri IV. Used the frequency of recombination between the gene pair in the same chromosome

Choose the correct answer from the options given below:
1. A-III   B-I      C-II     D-IV
2. A-III   B- IV   C-II     D-I
3. A-IV   B-III    C-II     D-I
4. A-II     B-III   C-I      D-IV
 
Subtopic:  Chromosomal Basis of Inheritance: Introduction | Chromosomal Basis of Inheritance: Further Considerations | Recombination & Gene Mapping | Mendelian Disorders |
Level 4: Below 35%
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If two plants having heterozygous genotype for a trait are crossed, what percentage of the progeny will have heterozygous genotype?
1.  25%
2.  50%
3.  75%
4.  100%
Subtopic:  Monohybrid Cross: 1 | Monohybrid Cross: Further Understanding |
 86%
Level 1: 80%+
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Phenylketonuria is a
1.  Sex-linked dominant disease
2.  Autosomal dominant disease
3.  Sex-linked recessive disease
4.  Autosomal recessive disease
Subtopic:  Mendelian Disorders |
 82%
Level 1: 80%+
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Which of the following are true of sex linked inhertiance in humans?
A. Males are considered to be hemizygous for genes present on X-chromosome
B. Majority of sex-linked traits are carried on the X-chromosome
C. Genes that are not sex-linked are present in somatic cells and absent in germ cells
D. 1:1 ratio of males and females in humans is a result of meiosis in males
E. The single X-chromosome present in the father is inherited by the son (male-to-male transmission)
Choose the correct answer from the options given below:
1.  A and B only
2.  B and D only
3.  A, B and C only
4.  B, D and E only
Subtopic:  Sex Determination |
Level 3: 35%-60%
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Which of the following are true about the ABO blood groupings in humans?
A. It is regulated by multiple alleles
B. It shows a total of six different genotypes but only four different phenotypes
C. AB blood type is an example of incomplete dominance
D. Persons with O-blood type are considered as universal acceptors
E. A person cannot have O-blood type if his mother has A-blood type and father has B blood type

Choose the correct answer from the options given below:
1. B and E only
2. A and C only
3. A and B only
4. D and E only
Subtopic:  Monohybrid Cross: Further Understanding |
 85%
Level 1: 80%+
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