What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?
(a) Gastric juice will be deficient in chymosin
(b) Gastric juice will be deficient in pepsinogen
(c) In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin
(d) Enterokinase will not be released from the duodenal mucosa and so trypsinogen is not converted to trypsin
(c) The parietal cells (oxyntic cells) are large and most numerous on the side walls of gastric glands secrete hydrochloric acid and castle intrinsic factor. The peptic cells (zymogen) of gastric glands secrete gastric digestive enzymes as proenzymes-pepsinogen and prorennin and small amount of gastric amylase and gastric lipase. The hydrochloric acid maintains a strongly acidic pH of about 1.5-2.5 in the stomach. HCI converts pepsinogen and prorennin to pepsin and rennin respectively.