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Q. No.During DNA replication the leading and lagging strands are synthesized differently. The reason for this difference is:
1.
DNA polymerase can work only on one strand at a time
2.
The single-strand binding proteins cannot bind to both strands of DNA
3.
DNA ligase works only in the 3ʹ →5ʹ direction
4.
DNA polymerase can add new nucleotides only to the 3’ end of a growing strand
Subtopic: DNA Replication |
61%
Level 2: 60%+
Hints
Which radioactive isotope was used in Meselson and Stahl experiment to prove the semi-conservative mode of DNA replication?
| 1. | 35S | 2. | 32P |
| 3. | 15N | 4. | None |
Subtopic: Search for Genetic Material |
Level 3: 35%-60%
Hints
Consider the following two statements:
| I: | During transcription, the template strand is read in a 3'-to-5' direction. |
| II: | During transcription, an RNA is transcribed in the 5'-to-3' direction. |
The correct statements is/are:
| 1. | I only | 2. | II Only |
| 3. | I and II | 4. | None |
Subtopic: Transcription: I |
79%
Level 2: 60%+
Hints
In eukaryotes, RNA polymerase III transcribes:
| 1. | hnRNA, snRNAs and 5.8S RNA |
| 2. | tRNA, 5.8S RNA and snRNAs |
| 3. | tRNA, 5SrRNA and snRNAs |
| 4. | rRNAs – 28S, 18S and 5S |
Subtopic: Transcription: I |
73%
Level 2: 60%+
Hints
For the multiplication of any alien piece of DNA in an organism it needs to be a part of a chromosome that has a specific:
1. Telomeric sequence
2. Multiple cloning site
3. Ori
4. Selectable marker
1. Telomeric sequence
2. Multiple cloning site
3. Ori
4. Selectable marker
Subtopic: DNA Replication |
90%
Level 1: 80%+
Hints
The UTR [untranslated regions] in an mRNA:
| 1. | Are present only at 5’ end and are not required for efficient translation |
| 2. | Are present only at 3’ end and are not required for efficient translation |
| 3. | Are present at both 5’ and 3’ends and are not required for efficient translation |
| 4. | Are present at both 5’ and 3’ ends and are required for an efficient translation process |
Subtopic: Translation Mechanism |
80%
Level 1: 80%+
Hints
In actual structure, tRNA is a compact molecule that looks like a/an:
| 1. | Cloverleaf | 2. | Railroad |
| 3. | Inverted L | 4. | Alpha helix |
Subtopic: Translation |
73%
Level 2: 60%+
Hints
Which of the following acts as a ribozyme for peptide bond formation in bacteria?
1. 5s rRNA
2. 23s rRNA
3. 16s rRNA
4. 5.1s rRNA
1. 5s rRNA
2. 23s rRNA
3. 16s rRNA
4. 5.1s rRNA
Subtopic: Translation |
87%
Level 1: 80%+
Hints
Which of the following acts as the substrate and provides energy for DNA replication?
| 1. | Dideoxyribonucleoside triphospahtes |
| 2. | Ribonucleoside triphosphates |
| 3. | Deoxyribonucleoside triphospahtes |
| 4. | Deoxyribonucleotide triphosphates |
Subtopic: DNA Replication: I |
64%
Level 2: 60%+
Hints
Who proposed a semi-conservative mode of replication for DNA?
| 1. | Watson and Crick | 2. | Meselson and Stahl |
| 3. | Hershey and Chase | 4. | Beadle and Tatum |
Subtopic: DNA vs RNA as Genetic Material |
63%
Level 2: 60%+
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