A person with sickle-cell anaemia is

1. more prone to malaria
2. more prone to typhoid
3. less prone to malaria
4. less prone to typhoid

(c) Sickle-cell anaemia is related to malaria not to typhoid and person suffering from

sickle-cell anaemia are resistant to malarial parasite ar RBC of sickle-cell anaemic
patients is distored in shape that not affected by Plasmodium sp.

it is known that heterozygotes Hbs/HBA, having both types of haemoglobin show
resistance to malarial infection because the body targets the P. falciparum infected cells
for destruction.

In contrast, individuals homozygous for normal haemoglobin (HbA/HbA) suffer high
mortality rates in early childhood due to malarial infection.