The first clinical gene therapy was done for the treatment of

1. AIDS
2. Cancer
3. Cystic fibrosis
4. SCID (Severe Combined Immuno Deficiency resulting from the deficiency of ADA



 

(4) The first clinical gene therapy was done for the treatment of SCID (Severe Combined Immuno Deficiency) resulting from the deficiency of ADA.

The SCID patient has a defective gene for the enzyme Adenosine Deaminase (ADA) due to which he/she lacks functional T-lymphocytes and therefore, fails to fight the infecting pathogen.