36. Name the site(s) of pyruvate synthesis. Also, write the chemical reaction where in pyruvic acid dehydrogenase acts as a catalyst.

 


Pyruvate is synthesised in cytoplasm of the cell by the process of glycolysis. 1 molecule of glucose forms 2 molecules of pyruvate through a series of reactions.
Pyruvic acid dehydrogenase catalyses the reaction in which pyruvate forms acetyl Co-A.It requires NAD+ , Co-enzyme A and Mg2+ ions forits activity. The reaction is as follows
 Pyruvic acid + Co-A + NAD+Pyruvate dehydrogenaseMg2+ Acetyl Co-A + NADH + H++ CO2