The compound that causes general antidepressant action on the central nervous system is known as -

1. Analgesics

2. Tranquilizers

3. Narcotic analgesics

4. Antihistamines

 
HINT: Tranquilizers are used as antidepressants.
Explanation: Analgesics reduces or abolishes pain without causing impairment of consciousness, mental confusion, incoordination or paralysis, or some other disturbances of the nervous system.

Analgesics are non-narcotic or narcotic. Narcotic analgesics when administered in small doses relieve pain and produce sleep.

Tranquilizers are a class of chemical compounds used for the treatment of stress and mild or even severe mental diseases.

Histamine is a substance which on release produces hypersensitivity to dust, some drugs, etc. (i.e., allergy).

Antihistamines are the drugs that interfere with the natural action of histamine by competing with histamine for binding sites of receptors where histamine exerts its effect. They are anti-allergy drugs.