Which of the carbon atoms present in the molecule given below are asymmetric?

1. 1, 2, 3, 4   
2. 2, 3     
3. 1, 4   
4. 1, 2, 3

Chiral/asymmetric carbon will indicate carbon where four diffrent atoms or groups are present. In the given molecule,

2nd and 3rd carbon are bonded to four different groups, hence these are asymmetric or chiral.