#30-Mendelian-Disorders
(Botany) > Principles of Inheritance & Variation

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What is the mode of inheritance of phenylketonuria?

1. Autosomal recessive

2. Autosomal dominant

3. Sex linked recessive

4. Sex linked dominant

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Match each item in Column I with one item in Column II and chose your answer from the codes given below:

Column I

Disorder

Column II

Feature

I. Phenylketonuria

II. Sickle Cell anemia

III. Down's Syndrome

IV. Turner's Syndrome

(i) Rudimentary ovaries

(ii) Gynecomastia

(iii) Trisomy 21

(iv) Lack of enzyme PAH

(v) Lack of tyrosinase

(vi) Mutation GAG to GUG

(vii) Mutation GUG to GAG

 

1. I - v; II - vii; III - iii; IV - i

2. I - iv; II - vi; III - iii; IV - i

3. I - v; II - vi; III - iii; IV - ii

4. I - v; II - vi; III - iii; IV - i

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Two phenotypically normal individuals have an affected child. What can we conclude about the parents?

1. they both carried the diesease allele

2. they are not the parents of the child

3. they are affected

4. no conclusions can be drawn

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Pick out the correct statements.

I. Haemophilia is a sex-linked recessive disease

II. Down's syndrome is due to aneuploidy.

III. Phenylketonuria is an autosomal recessive gene disorder

IV. Sickle cell anaemia is an x - linked recessive gene disorder

(1) II and IV are correct

(2) I, III and IV are correct

(3) I, II and III are correct

(4) I and IV are correct

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Which of the following is not an autosomal genetic disorder ?

(1) Sickle-cell anaemia

(2) Cystic fibrosis

(3) Haemophilia

(4) Huntington's disease

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