Which of the following are the reason(s) for rheumatoid arthritis? Choose the correct option.
| I. | Lymphocytes become more active |
| II. | Body attacks self cells |
| III. | More antibodies are produced in the body |
| IV. | The ability to differentiate pathogens or foreign molecules from self-cells is lost |
1. I and II
2. II and IV
3. III and IV
4. I and III
| Assertion(A): | Histamine is involved in allergic and inflammatory reactions. |
| Reason(R): | Histamine is a vasodilator. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion(A): | Organ transplantation patients are given immunosuppressive drugs. |
| Reason(R): | Transplanted tissue has antigens which stimulate the specific immune response of the recipient. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion(A): | Allergens in the environment on reaching human body stimulate mast cells in certain individuals. |
| Reason(R): | Mast cells in human body release excess amount of inflammatory chemicals which cause allergic reactions. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion(A): | Blood cells involved in inflammatory reactions are basophils. |
| Reason(R): | Antibodies in our body are complex glycoproteins. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion (A): | Sudden sneezing and wheezing are symptoms of allergy to pollen, mites, etc. |
| Reason (R): | Some of us are sensitive to some particles in the environment. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |