Assertion: Nicotine binds directly to the receptors on the postsynaptic neurons of the brain.
Reason: Any chemical occurring in the brain will naturally have receptors on the neurons.

1. Both assertion and reason are true and the reason is the correct explanation of the assertion.
2. Both assertion and reason are true but the reason is not the correct explanation of the assertion.
3. Assertion is true but reason is false.
4. Both assertion and reason are false.

What would be true for the nociceptors?

1. Nociceptors respond to extreme stimuli

2. All nociceptors are located in the skin

3. Nociceptors are involved in noise perception

4. Nociceptor pathways of conduction cannot be inhibited

A drug acts as an inhibitor of acetylcholinesterase. Administration of this drug would lead to:
1. accumulation of acetylcholine in the synaptic cleft
2. accumulation of acetylcholinesterase in the synaptic cleft
3. muscle relaxation
4. repeated action potentials

Assertion: Nerve gas Sarin and agricultural insecticide Parathion can cause severe spastic paralysis in humans.
Reason: Sarin and Parathion act as inhibitors of the enzyme choline acetyl transferase.

1. Both assertion and reason are true and the reason is the correct explanation of the assertion.
2. Both assertion and reason are true but the reason is not the correct explanation of the assertion.
3. Assertion is true but reason is false.
4. Both assertion and reason are false.

Alzheimer’s disease in humans is associated with the deficiency of
1. dopamine
2. glutamic acid
3. acetylcholine
4. Gamma Amino Butyric Acid (GABA)