| 1. | Inflammation of joints due to accumulation of uric acid crystals |
| 2. | Weakening of bones due to decreased bone mass |
| 3. | Inflammation of joints due to cartilage degeneration |
| 4. | Weakening of bones due to low calcium level |
| 1. | Actin and myosin filaments slide over each other to increase the length of the sarcomere. |
| 2. | Length of A–band does not change. |
| 3. | I–band increases in length |
| 4. | The actin filaments slide away from A–band resulting in shortening of sarcomere |
Which of the following is correct statement ?
| 1. | Actin and regulatory proteins are located in thin filament. |
| 2. | Z-lines anchor myosin (thick) filament to the ends of the sarcomere. |
| 3. | Sarcoplasmic reticulum stores acetylcholine. |
| 4. | Myosin cross bridges contain calcium binding sites. |
| 1. | Muscular dystrophy | An auto immune disorder causing progressive degeneration of skeletal muscle |
| 2. | Arthritis | Inflamed joints |
| 3. | Tetany | high Ca2+ level causing rapid spasms. |
| 4. | Myasthenia gravis | Genetic disorder resulting in weakening and paralysis of skeletal muscle |
| Assertion (A): | Osteoporosis is characterised by decreased bone mass and increased chances of fractures. |
| Reason (R): | Common cause of osteoporosis is increased levels of estrogen. |
| 1. | (A) is not correct but (R) is correct. |
| 2. | Both (A) and (R) are correct and (R) is the correct explanation of (A). |
| 3. | Both (A) and (R) are correct but (R) is not the correct explanation of (A). |
| 4. | (A) is correct but (R) is not correct. |
| List-I (Type of Joint) |
List-II (Found between) |
||
| A. | Cartilaginous Joint | I. | Between flat skull bones |
| B. | Ball and Socket Joint | II. | Between adjacent vertebrae in vertebral column |
| C. | Fibrous Joint | III. | Between carpal and metacarpal of thumb |
| D. | Saddle Joint | IV. | Between Humerus and Pectoral girdle |
| Options: | A | B | C | D |
| 1. | II | IV | III | I |
| 2. | III | I | II | IV |
| 3. | II | IV | I | III |
| 4. | I | IV | III | II |
| A: | Muscle bundles are held together by collagenous connective tissue layer called fascicle. |
| B: | Sarcoplasmic reticulum of muscle fibre is a store house of calcium ions. |
| C: | Striated appearance of skeletal muscle fibre is due to distribution pattern of actin and myosin proteins. |
| D: | M line is considered as functional unit of contraction called sarcomere. |
| 1. | C and D only | 2. | A, B and C only |
| 3. | B and C only | 4. | A, C and D only |
| List-I | List-II | ||
| (A) | Palm bones | (I) | Phalanges |
| (B) | Wrist bones | (II) | Metacarpals |
| (C) | Ankle bones | (III) | Carpals |
| (D) | Digit bones | (IV) | Tarsals |
| Options: | (A) | (B) | (C) | (D) |
| 1. | II | III | I | IV |
| 2. | IV | I | II | III |
| 3. | III | IV | I | II |
| 4. | II | III | IV | I |
During muscular contraction, which of the following events occur?
| (a) | 'H' zone disappears |
| (b) | 'A' band widens |
| (c) | 'I' band reduces in width |
| (d) | Myosin hydrolyzes ATP, releasing the ADP and Pi |
| (e) | Z-lines attached to actins are pulled inwards |
Choose the correct answer from the options given below:
1. (b), (c), (d) and (e) only
2. (b), (d), (e) and (a) only
3. (a), (c), (d) and (e) only
4. (a), (b), (c) and (d) only