Read the following statements carefully.
(i) PCR is used to detect mutations in genes in suspected cancer patients.
(ii) A direct method to insert a foreign gene into plant cells is micro-injection.
(iii) The first transgenic cow, Rosie, produced human protein-enriched milk, i.e., 5.4 grams per litre.
(iv) RNAi takes place in all eukaryotic organisms as a method of cellular defense.
How many of the above statements are correct?
1. 1
2. 2
3. 3
4. 4
Subtopic:  Molecular Diagnosis | Transgenic Microbes & Animals |
 57%
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Which combinations of DNA could be present in a transgenic organism?
(i) invertebrate animal DNA in mammal DNA
(ii) prokaryotic DNA in plant DNA
(iii) plant DNA in animal DNA
1. (i), (ii) and (iii)
2. (ii) and (iii) only
3. (i) and (iii) only
4. (i) and (ii) only
 
Subtopic:  Transgenic Microbes & Animals |
 50%
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From the list of human diseases given below, which ones have transgenic models existing for them? 
a. Alzheimer's 
b. Rheumatoid arthritis
c. Cystic fibrosis 
d. Cancer 
Select the correct option from the following 
1. b and c only 
2. a only 
3. d and a only 
4. a, b, c and d 
Subtopic:  Transgenic Microbes & Animals |
 84%
From NCERT
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Assertion(A): 95% of the existing transgenic animals are mice.
Reason(R): They are important live tools for researching human disease, being used to understand gene function in context of disease susceptibility, progression and to determine responses to a therapeutic intervention.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Transgenic Microbes & Animals |
 77%
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Assertion(A): Transgenic animals can be specifically designed to allow the study of how genes are regulated.
Reason(R): Gene regulation can be studied only in the transgenic animals.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Transgenic Microbes & Animals |
 53%
From NCERT
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Assertion(A): The transgenic cow, Rosie, could produce human alpha-lactalbumin.
Reason(R): This milk is nutritionally more balanced product for human babies than the baby's mother.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Transgenic Microbes & Animals |
From NCERT
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Assertion(A): Transgenic mice are being developed for use in testing the safety of vaccines before they are used on humans.
Reason(R): Transgenic mice are being used to test the safety of polio vaccine.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Transgenic Microbes & Animals |
 70%
From NCERT
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Assertion(A): For toxicity testing, transgenic animals are exposed to the toxic substances and the effect is studied.
Reason(R): Transgenic animals are made to carry genes which make them more sensitive to toxic substances than non transgenic animals.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Transgenic Microbes & Animals |
 77%
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Find the true (T)/false (F) statements and choose the correct option.
I. GMO may lead to health risk in humans
II. Interferons were discovered by Issacs and Lindenmann
III. Interferons can cure AIDS
IV. Antibodies derived from a single clone of cells which recognize only one kind of antigen, are called monoclonal antiobodies
I II III IV
1. T T F T
2. T T T T
3. F T T T
4. T F F T
Subtopic:  Gene Therapy | Transgenic Microbes & Animals |
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