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Q. No.Assertion (A): In 1983, Eli Lilly used E.coli, as heterologous host for the production of humulin
Reason (R): Production of insulin in E.coli by genetic engineering is possible because bacterial cells can carry out the RNA splicing mechanism
Choose the correct answer from the options given below
1. Both (A) and (R) are true and (R) is the correct explanation of the (A)
2. Both (A) and (R) are true but (R) is not the correct explanation of the (A)
3. (A) is true but (R) us false
4. (A) is false but (R) is true
Subtopic: Â Med Applications & Humulin |
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From the list of human diseases given below, which ones have transgenic models existing for them?
a. Alzheimer's
b. Rheumatoid arthritis
c. Cystic fibrosis
d. Cancer
Select the correct option from the following
1. b and c only
2. a only
3. d and a only
4. a, b, c and d
a. Alzheimer's
b. Rheumatoid arthritis
c. Cystic fibrosis
d. Cancer
Select the correct option from the following
1. b and c only
2. a only
3. d and a only
4. a, b, c and d
Subtopic: Â Transgenic Microbes & Animals |
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With regard to insulin choose the incorrect statement(s).
Choose the correct answer from the options given below.
1. (a) and (b) only
2. (c) and (d)
3. (a), (b) and (c)
4. (d) only
| a. | C-peptide is found attached with both A and B chains of insulin with the help of disulphide bonds. |
| b. | In 1983, both A and B chains were produced by introducing alien genes in plasmid of same E.coli by Eli Lilly. |
| c. | A-peptide and B-peptide of insulin are interconnected by peptide bonds in mature insulin. |
| d. | Insulin from an animal source may cause allergy or other types of reactions in some diabetic patients. |
1. (a) and (b) only
2. (c) and (d)
3. (a), (b) and (c)
4. (d) only
Subtopic: Â Med Applications & Humulin |
 56%
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| Assertion (A): | Insulin used for diabetes was earlier extracted from the pancreas of slaughtered cattle and pigs but now it is not used. |
| Reason (R): | Aarti along with some other patients took insulin injections in which insulin was from an animal source and they manifested an allergic response to that. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
Subtopic: Â Med Applications & Humulin |
 81%
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Assertion: Functional ADA cDNA genes must be inserted in the lymphocytes at the early embryonic stage to treat SCID.
Reason: Cells in the embryonic stage are mortal, differentiated and easy to manipulate.
1. Both A and R are true and R is the correct explanation of A.
2. Both A and R are true and R is not the correct explanation of A.
3. A is true but R is false.
4. A is False but R is true.
Reason: Cells in the embryonic stage are mortal, differentiated and easy to manipulate.
1. Both A and R are true and R is the correct explanation of A.
2. Both A and R are true and R is not the correct explanation of A.
3. A is true but R is false.
4. A is False but R is true.
Subtopic: Â Gene Therapy |
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Assertion(A): Agrobacterium tumefaciens is popular in genetic engineering because this bacterium is associated with the roots of all cereal and pulse crops.
Reason(R): A gene incorporated in the bacterial chromosomal genome gets automatically transferred to the crop with which the bacterium is associated.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): A gene incorporated in the bacterial chromosomal genome gets automatically transferred to the crop with which the bacterium is associated.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Intro to Agri Applications |
From NCERT
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Assertion(A): Agrobacterium tumifaciens is common pathogen of plant family poaceae.
Reason(R): Plants of poaceae family are highly sensitive to the bacteria Agrobacterium tumifaciens.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): Plants of poaceae family are highly sensitive to the bacteria Agrobacterium tumifaciens.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Bt Crops |Â Interference RNA Tech |
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Assertion(A): Batch fermentation is said to be closed system.
Reason(R): In batch fermentation, the conditions set up are not changed from outside one fermentation starts.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): In batch fermentation, the conditions set up are not changed from outside one fermentation starts.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Med Applications & Humulin |
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Assertion(A): A gene from Bacillus thuringiensis is incorporated in plant genome to increase their yield.
Reason(R): Bacillus thuringiensis has Bt toxin producing gene, which kills the larva of insects.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): Bacillus thuringiensis has Bt toxin producing gene, which kills the larva of insects.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Intro to Agri Applications |Â Bt Crops |
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Assertion(A): Plantbody is an antibody.
Reason(R): It is an antibody produced by plants that have been genetically engineered with animal DNA.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Reason(R): It is an antibody produced by plants that have been genetically engineered with animal DNA.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic: Â Vaccines |Â Molecular Diagnosis |
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