Q. No.Which of the following therapies for ADA deficiency are not completely curative?
(1) Bone Marrow Transplantation
(2) Enzyme replacement Therapy
(3) Both A and B
(4) Both are completely curative
(1) Bone Marrow Transplantation
(2) Enzyme replacement Therapy
(3) Both A and B
(4) Both are completely curative
The first step of gene therapy would be
(1) Culture of the lymphocytes from patient's blood
(2) Using vector for transmitting gene
(3) cDNA was prepared
(4) cDNA was inserted directly into the cells
The last step of gene therapy would be
(1) The corrected lymphocytes are returned to the patients
(2) Culture of lymphocytes of the patient
(3) Introduction of correct gene in cultured cells
(4) Removal of corrected lymphocytes from culture
The permanent cure of gene therapy can be
(1) Cells isolated from bone marrow in an adult were cultured and transformed with corrected gene
(2) Cells isolated from thymus in an adult were cultured and transformed with corrected gene
(3) Cells isolated from bone marrow in an embryo were cultured and transformed with corrected gene
(4) Genes isolated from bone marrow were introduced into the cells at early embryonic stage
Conventional methods are not
1. Serum analysis
2. Urine analysis
3. For early detection
4. Both 2 and 3
PCR will allow to detect genetic defects but doesn't involve which of the following steps.
(1) Probing with radioactive molecule
(2) Hybridization
(3) Autoradiography
(4) Antigen antibody interaction
Consider the following statements:
| I: | RNAi takes place in all eukaryotic organisms as a method of cellular defense. |
| II: | It involves the silencing of a specific mRNA due to complementary dsDNA molecules that prevent the translation of mRNA. |
| III: | Fire and Mello got the Nobel Prize for the discovery of RNAi. |
Which of the above statements are true?
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
Gene therapy is not
(1) An attempt to correct a gene defect
(2) By which genes are inserted into an individual or embryo to take over the function of and compensate the non-functional gene.
(3) Genes are inserted into a person's cells and tissues to treat a disease
(4) Correction of environmental defect by inserting a gene
Insulin chains produced by Eli Lilly using recombinant DNA technology, actually taken which of the following strain of bacteria?
(1) Escherichia coli
(2) Bacillus subtilis
(3) Saccharomyces cerevisiae
(4) Bacillus xenus
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